Biocatalytic Transformations of Steroids: Focus on Hydrolase-Catalyzed Reactions (Articolo in rivista)

Type
Label
  • Biocatalytic Transformations of Steroids: Focus on Hydrolase-Catalyzed Reactions (Articolo in rivista) (literal)
Anno
  • 2011-01-01T00:00:00+01:00 (literal)
Alternative label
  • Manuel Cruz Silva, M.; Carvalho, Joao F.; Riva, Sergio; Luisa Sa e Melo, M. (2011)
    Biocatalytic Transformations of Steroids: Focus on Hydrolase-Catalyzed Reactions
    in Current organic chemistry
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Manuel Cruz Silva, M.; Carvalho, Joao F.; Riva, Sergio; Luisa Sa e Melo, M. (literal)
Pagina inizio
  • 928 (literal)
Pagina fine
  • 941 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 15 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 14 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 6 (literal)
Note
  • ISI Web of Science (WoS) (literal)
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Universidade de Coimbra; Ist Chim Riconoscimento Mol (literal)
Titolo
  • Biocatalytic Transformations of Steroids: Focus on Hydrolase-Catalyzed Reactions (literal)
Abstract
  • Steroids comprise several classes of structurally related molecules with multiple bioactivities. Due to their complexity, the selective modification of these polycyclic compounds is challenging. This review outlines recent developments in the use of biocatalysts for the transformation of steroids, specifically focusing on the synthetic exploitation of hydrolases. Accordingly, several regio- and stereoselective acylations and deacylations mediated by lipases and proteases are discussed en route to preparation of new derivatives with useful application in pharmaceutical and food chemistry. (literal)
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