Evaluation of amphetamine-induced hyperlocomotion and catalepsy following long-acting risperidone administration in rats. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Evaluation of amphetamine-induced hyperlocomotion and catalepsy following long-acting risperidone administration in rats. (Articolo in rivista) (literal)

Anno

• 2009-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.ejphar.2009.07.024 (literal)

Alternative label

• Marchese G a,b; Casu G b; Casti P b; Spada GP b; Pani L a,b (2009)
  Evaluation of amphetamine-induced hyperlocomotion and catalepsy following long-acting risperidone administration in rats.
  in European journal of pharmacology; Editore: Elsevier, Oxford (Regno Unito)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Marchese G a,b; Casu G b; Casti P b; Spada GP b; Pani L a,b (literal)

Pagina inizio

• 36 (literal)

Pagina fine

• 41 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.elsevier.com/locate/ejphar (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 620 (literal)

Rivista

• European journal of pharmacology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 6 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1-3 (literal)

Note

• PubMe (literal)
• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• a C.N.R., Institute of Biomedical Technology, Sect. Cagliari, Technological Park of Sardinia\"Sardegna Ricerche\", Pula, Cagliari, Italy; b Pharmaness S.c.a r.l., Technological Park of Sardinia\"Sardegna Ricerche\", Pula, Cagliari, Italy (literal)

Titolo

• Evaluation of amphetamine-induced hyperlocomotion and catalepsy following long-acting risperidone administration in rats. (literal)

Abstract

• It has been proposed that long-acting risperidone could provide a constant antipsychotic efficacy associated with a reduced liability to induce extra-pyramidal symptoms. To ascertain this hypothesis, antagonism of amphetamine-induced hyperlocomotion and catalepsy were analyzed in rats for a period of 1-6 weeks following long-acting risperidone (20-60 mg/kg) injection. Long-acting risperidone reduced amphetamine-induced hyperlocomotion after 2-5 weeks from drug injection, without producing significant extra-pyramidal symptoms. Following the administration of long-acting risperidone a constant ability to antagonize amphetamine-induced hyperlocomotion was observed during the day, but not when the antipsychotic was chronically administered using a short-acting formulation. The pre-clinical results confirmed that long-acting risperidone may represent an advance in antipsychotic therapy. (literal)

Editore

• Editore: Elsevier (Editore)

Prodotto di

• Drug design, drug delivery e valutazione preclinica di nuove entità chimiche. (ME.P06.020.001) (Modulo)

Autore CNR

• LUCA PANI (Persona)
• GIORGIO MARCHESE (Persona)

Insieme di parole chiave

• Parole chiave di "Evaluation of amphetamine-induced hyperlocomotion and catalepsy following long-acting risperidone administration in rats." (Insieme di parole chiave)

Incoming links:

Autore CNR di

• GIORGIO MARCHESE (Persona)
• LUCA PANI (Persona)

Prodotto

• Drug design, drug delivery e valutazione preclinica di nuove entità chimiche. (ME.P06.020.001) (Modulo)

Editore di

• Editore: Elsevier (Editore)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• European journal of pharmacology (Rivista)

Insieme di parole chiave di

• Parole chiave di "Evaluation of amphetamine-induced hyperlocomotion and catalepsy following long-acting risperidone administration in rats." (Insieme di parole chiave)