http://www.cnr.it/ontology/cnr/individuo/prodotto/ID175877
Scaling exponents and probability distributions of DNA end-to-end distance (Articolo in rivista)
- Type
- Label
- Scaling exponents and probability distributions of DNA end-to-end distance (Articolo in rivista) (literal)
- Anno
- 2005-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1103/PhysRevLett.95.158105 (literal)
- Alternative label
Francesco Valle (1), Mélanie Favre (1), Paolo De Los Rios (2), Angelo Rosa (3), Giovanni Dietler (1) (2005)
Scaling exponents and probability distributions of DNA end-to-end distance
in Physical review letters (Print); American Physical Society (APS), College Pk (Stati Uniti d'America)
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Francesco Valle (1), Mélanie Favre (1), Paolo De Los Rios (2), Angelo Rosa (3), Giovanni Dietler (1) (literal)
- Pagina inizio
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
- http://link.aps.org/doi/10.1103/PhysRevLett.95.158105 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
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- ISI Web of Science (WOS) (literal)
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- (1)Laboratory of Physics of Living Matter, IPMC, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland
(2)Laboratory of Statistical Biophysics, ITP, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland
(3)Laboratory for Computation and Visualization in Mathematics and Mechanics, IMB, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland (literal)
- Titolo
- Scaling exponents and probability distributions of DNA end-to-end distance (literal)
- Abstract
- The scaling of the average gyration radius of polymers as a function of their length can be experimentally determined from ensemble measurements, such as light scattering, and agrees with analytical estimates. Ensemble techniques, yet, do not give access to the full probability distributions. Single molecule techniques, instead, can deliver information on both average quantities and distribution functions. Here we exploit the high resolution of atomic force microscopy over long DNA molecules adsorbed on a surface to measure the average end-to-end distance as a function of the DNA length, and its full distribution function. We find that all the scaling exponents are close to the predicted 3D values (?=0.589±0.006 and ?=2.58±0.77). These results suggest that the adsorption process is akin to a geometric projection from 3D to 2D, known to preserve the scaling properties of fractal objects of dimension df<2. (literal)
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