Neuroprotective effects of thymosin beta4 in Experimental Models of Excitotoxicity (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Neuroprotective effects of thymosin beta4 in Experimental Models of Excitotoxicity (Articolo in rivista) (literal)

Anno

• 2007-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1196/annals.1415.033 (literal)

Alternative label

• PATRIZIA POPOLI1; RITA PEPPONI1; ALBERTO MARTIRE1; MONICA ARMIDA1; ANTONELLA PÈZZOLA1; MARIANGELA GALLUZZO1; M. ROSARIA DOMENICI1; ROSA LUISA POTENZA1; M. TERESA TEBANO1; CRISTIANA MOLLINARI1; DANIELA MERLO1,2; ENRICO GARACI3 (2007)
  Neuroprotective effects of thymosin beta4 in Experimental Models of Excitotoxicity
  in Annals of the New York Academy of Sciences
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• PATRIZIA POPOLI1; RITA PEPPONI1; ALBERTO MARTIRE1; MONICA ARMIDA1; ANTONELLA PÈZZOLA1; MARIANGELA GALLUZZO1; M. ROSARIA DOMENICI1; ROSA LUISA POTENZA1; M. TERESA TEBANO1; CRISTIANA MOLLINARI1; DANIELA MERLO1,2; ENRICO GARACI3 (literal)

Pagina inizio

• 219 (literal)

Pagina fine

• 224 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 1112 (literal)

Rivista

• Annals of the New York Academy of Sciences (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1 Istituto Superiore di Sanità, Viale Regina Elena, Rome, Italy; 2 IRCCS San Raffaele Pisana, Rome, Italy; 3 Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Rome, Italy (literal)

Titolo

• Neuroprotective effects of thymosin beta4 in Experimental Models of Excitotoxicity (literal)

Abstract

• The aim of this study was to evaluate the possible neuroprotective effects of thymosin ?4 in different models of excitotoxicity. The application of thymosin ?4 significantly attenuated glutamate-induced toxicity both in primary cultures of cortical neurons and in rat hippocampal slices. In in vivo experiments, the intracerebroventricular administration of thymosin ?4 significantly reduced hippocampal neuronal loss induced by kainic acid. These results show that thymosin ?4 induced a protective effect in models of excitotoxicity. The mechanisms underlying such an effect, as well as the real neuroprotective potential of thymosin ?4, are worthy of further investigations. (literal)

Prodotto di

• Ricerca traslazionale ed outcome nelle patologie infiammatorie e degenerative (ME.P04.009.001) (Modulo)

Autore CNR

• CRISTIANA MOLLINARI (Unità di personale interno)

Insieme di parole chiave

• Parole chiave di "Neuroprotective effects of thymosin beta4 in Experimental Models of Excitotoxicity" (Insieme di parole chiave)

Incoming links:

Prodotto

• Ricerca traslazionale ed outcome nelle patologie infiammatorie e degenerative (ME.P04.009.001) (Modulo)

Autore CNR di

• CRISTIANA MOLLINARI (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Annals of the New York Academy of Sciences (Rivista)

Insieme di parole chiave di

• Parole chiave di "Neuroprotective effects of thymosin beta4 in Experimental Models of Excitotoxicity" (Insieme di parole chiave)