http://www.cnr.it/ontology/cnr/individuo/prodotto/ID173311
Nanostructured lipid carriers-containing anticancer compounds: preparation, characterization, and cytotoxicity studies (Articolo in rivista)
- Type
- Label
- Nanostructured lipid carriers-containing anticancer compounds: preparation, characterization, and cytotoxicity studies (Articolo in rivista) (literal)
- Anno
- 2007-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1080/10717540600739914 (literal)
- Alternative label
Bondì ML, Craparo EF, Giammona G, Cervello M, Azzolina A, Diana P, Martorana A, Cirrincione G. (2007)
Nanostructured lipid carriers-containing anticancer compounds: preparation, characterization, and cytotoxicity studies
in Drug delivery; Librapharm/Informa Healthcare, London (Regno Unito)
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Bondì ML, Craparo EF, Giammona G, Cervello M, Azzolina A, Diana P, Martorana A, Cirrincione G. (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- ISMN-CNR
DIPARTIMENTO DI CHIMICA E TECNOLOGIE FARMACEUTICHE-UNIPA
IBIM-CNR
DIPARTIMENTO FARMACOCHIMICO (literal)
- Titolo
- Nanostructured lipid carriers-containing anticancer compounds: preparation, characterization, and cytotoxicity studies (literal)
- Abstract
- This article describes the development of nanostructured lipid
carriers (NLC) as colloidal carriers for two antitumor compounds
that possess a remarkable antineoplastic activity. But their limited
stability and lowsolubility in water could give a very lowparenteral
bioavailability. Results revealed an enhancement of the cytotoxicity
effect of drug-loaded NLC on human prostate cancer (PC-3) and
human hepatocellular carcinoma (HuH-6, HuH-7) cell lines with
respect to that of both free drugs. Results of characterization studies
strongly support the potential application of these drugs-loaded
NLC as prolonged delivery systems for lipophilic drugs by several
administration routes, in particular for intravenous administration. (literal)
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- Prodotto di
- Autore CNR
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