http://www.cnr.it/ontology/cnr/individuo/prodotto/ID172557
Mechanical properties of zona pellucida hardening (Articolo in rivista)
- Type
- Label
- Mechanical properties of zona pellucida hardening (Articolo in rivista) (literal)
- Anno
- 2010-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1007/s00249-009-0468-3 (literal)
- Alternative label
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Massimiliano Papi1; Roberto Brunelli2; Lakamy Sylla3; Tiziana Parasassi4; Maurizio Monaci3; Giuseppe Maulucci1; Mauro Missori1,6; Giuseppe Arcovito1; Fulvio Ursini5; Marco De Spirito1 (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
- http://link.springer.com/article/10.1007%2Fs00249-009-0468-3 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
- 2009 May 27. [Epub ahead of print] (Sp. Iss. SI). Springer. From the issue entitled \"Special Issue: Proceedings of the XIX Congress, Italian Society of Pure and Applied Biophysics (SIBPA), Rome September 17-20, 2008, Guest Editor: Daniela Giacomazza\". (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
- Note
- PubMe (literal)
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- 1 Istituto di Fisica, Università Cattolica del S. Cuore, L.go F. Vito 1, 00168 Rome, Italy;
2 Dipartimento di Scienze Ginecologiche, Perinatologia e Puericultura, Università di Roma Sapienza, P.le Aldo Moro 5, 00185 Rome, Italy;
3 Dipartimento di Patologia, Diagnostica e Clinica Veterinaria, Università di Perugia, Via San Costanzo 4, 06126 Perugia, Italy;
4 Istituto di Neurobiologia e Medicina Molecolare, Consiglio Nazionale delle Ricerche, Via del Fosso del Cavaliere 100, 00133 Rome, Italy;
5 Dipartimento di Chimica Biologica, Università di Padova, V.le Colombo 3, 35131 Padova, Italy
[(6) CNR-ISC, Tor Vergata, Roma] vedere ID 57533 (literal)
- Titolo
- Mechanical properties of zona pellucida hardening (literal)
- Abstract
- We have investigated the changes in the mechanical properties of the zona pellucida (ZP), a multilayer glycoprotein coat that surrounds mammalian eggs, that occur after the maturation and fertilization process of the bovine oocyte by using atomic force spectroscopy. The response of the ZP to mechanical stress has been recovered according to a modified Hertz model. ZP of immature oocytes shows a pure elastic behavior. However, for ZPs of matured and fertilized oocyte, a transition from a purely elastic behavior, which occurs when low stress forces are applied, towards a plastic behavior has been observed. The high critical force necessary to induce deformations, which supports the noncovalent long interaction lifetimes of polymers, increases after the cortical reaction. Atomic force microscopy (AFM) images show that oocyte ZP surface appears to be composed mainly of a dense, random meshwork of nonuniformly arranged fibril bundles. More wrinkled surface characterizes matured oocytes compared with immature and fertilized oocytes. From a mechanical point of view, the transition of the matured ZP membrane toward fertilized ZP, through the hardening process, consists of the recovery of the elasticity of the immature ZP while maintaining a plastic transition that, however, occurs with a much higher force compared with that required in matured ZP. (literal)
- Prodotto di
- Autore CNR
- Insieme di parole chiave
Incoming links:
- Autore CNR di
- Prodotto
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
- Insieme di parole chiave di
