Stress/Rest Myocardial Perfusion Abnormalities by Gated SPECT: Still the Best Predictor of Cardiac Events in Stable Ischemic Heart Disease (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Stress/Rest Myocardial Perfusion Abnormalities by Gated SPECT: Still the Best Predictor of Cardiac Events in Stable Ischemic Heart Disease (Articolo in rivista) (literal)

Anno

• 2009-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.2967/jnumed.108.055954 (literal)

Alternative label

• Alessia Gimelli; Giuseppe Rossi; Patrizia Landi; Paolo Marzullo; Giorgio Iervasi; Antonio L'Abbate; Daniele Rovai. (2009)
  Stress/Rest Myocardial Perfusion Abnormalities by Gated SPECT: Still the Best Predictor of Cardiac Events in Stable Ischemic Heart Disease
  in The Journal of nuclear medicine (1978)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Alessia Gimelli; Giuseppe Rossi; Patrizia Landi; Paolo Marzullo; Giorgio Iervasi; Antonio L'Abbate; Daniele Rovai. (literal)

Pagina inizio

• 546 (literal)

Pagina fine

• 553 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://jnm.snmjournals.org/content/50/4/546.long (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 50 (literal)

Rivista

• ?The ?Journal of nuclear medicine (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• In: Journal of Nuclear Medicine, vol. 50 pp. 546 - 553. Society of Nuclear Medicine, Inc, 2009. (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 4 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• CNR, Istituto di Fisiologia Clinica, Pisa, Italy Fondazione Gabriele Monasterio, Pisa, Italy Scuola Superiore Sant'Anna, Pisa, Italy (literal)

Titolo

• Stress/Rest Myocardial Perfusion Abnormalities by Gated SPECT: Still the Best Predictor of Cardiac Events in Stable Ischemic Heart Disease (literal)

Abstract

• The prognostic power of myocardial perfusion imaging in patients with ischemic heart disease (IHD) has been demonstrated since planar imaging. We aimed to investigate whether gated SPECT retains this value in current cardiology if compared with a complete diagnostic work-up and with more recent prognostic indicators. Methods: We selected from our database a cohort of 676 consecutive inpatients who underwent a complete diagnostic work-up that included gated SPECT and coronary arteriography for known or suspected IHD. Patients with acute myocardial infarction (MI), previous coronary artery bypass surgery, or overt hyperthyroidism and patients who were undergoing dialysis treatment were excluded. During follow-up (median, 37 mo), 24 patients died from cardiac causes and 19 experienced a nonfatal MI. Results: The following were determined to be independent predictors of event-free survival (cardiac death and nonfatal MI) in the different phases of diagnostic work-up using Cox proportional hazards regression analysis: among clinical variables, a previous MI; among laboratory examinations, serum creatinine and low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol levels; among electrocardiographic and echocardiographic variables, left ventricular ejection fraction; and among SPECT variables, summed rest score (SRS) and summed difference score (SDS). In addition, a score of coronary stenoses at angiography was an independent predictor. When the above predictors were tested together, SRS (P , 0.0001), SDS (P 5 0.0108), and serum creatinine (P 5 0.0186) and LDL and HDL cholesterol levels (P 5 0.0222) were the final independent predictors of event-free survival. When gated SPECT was added to the clinical, laboratory, electrocardiographic, and echocardiographic variables, the prognostic stratification significantly improved (P , 0.05); when coronary arteriography was added to gated SPECT, prognostic stratification did not further improve (P . 0.25). If t (literal)

Prodotto di

• Istituto di fisiologia clinica (IFC) (Istituto)

Autore CNR

• GIORGIO IERVASI (Unità di personale interno)
• GIUSEPPE ROSSI (Unità di personale interno)
• DANIELE ROVAI (Persona)
• ANTONIO L'ABBATE (Persona)
• PATRIZIA LANDI (Unità di personale interno)
• alessia gimelli (Unità di personale esterno)
• PAOLO MARZULLO (Persona)

Insieme di parole chiave

• Keywords of "Stress/Rest Myocardial Perfusion Abnormalities by Gated SPECT: Still the Best Predictor of Cardiac Events in Stable Ischemic Heart Disease" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• PAOLO MARZULLO (Persona)
• ANTONIO L'ABBATE (Persona)
• GIUSEPPE ROSSI (Unità di personale interno)
• DANIELE ROVAI (Persona)
• GIORGIO IERVASI (Unità di personale interno)
• PATRIZIA LANDI (Unità di personale interno)
• alessia gimelli (Unità di personale esterno)

Prodotto

• Istituto di fisiologia clinica (IFC) (Istituto)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• ?The ?Journal of nuclear medicine (Rivista)

Insieme di parole chiave di

• Keywords of "Stress/Rest Myocardial Perfusion Abnormalities by Gated SPECT: Still the Best Predictor of Cardiac Events in Stable Ischemic Heart Disease" (Insieme di parole chiave)