Simplified chemical and radiochemical synthesis of 2-arachidonoyl-glycerol, an endogenous ligand of cannabinoid receptors (Articolo in rivista)

Type
Label
  • Simplified chemical and radiochemical synthesis of 2-arachidonoyl-glycerol, an endogenous ligand of cannabinoid receptors (Articolo in rivista) (literal)
Anno
  • 2004-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.tetlet.2004.02.045 (literal)
Alternative label
  • Cartoni A., Margonelli A. 1, Angelini G., Finazzi-Agrò, Maccarone M. G. Angelini, A. Margonelli, A. Cartoni, A. Finazzi-Agrò, M. Maccarone (2004)
    Simplified chemical and radiochemical synthesis of 2-arachidonoyl-glycerol, an endogenous ligand of cannabinoid receptors
    in Tetrahedron letters
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Cartoni A., Margonelli A. 1, Angelini G., Finazzi-Agrò, Maccarone M. G. Angelini, A. Margonelli, A. Cartoni, A. Finazzi-Agrò, M. Maccarone (literal)
Pagina inizio
  • 2723 (literal)
Pagina fine
  • 2726 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 45 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1- CNR-IC, sede di Monterotondo (literal)
Titolo
  • Simplified chemical and radiochemical synthesis of 2-arachidonoyl-glycerol, an endogenous ligand of cannabinoid receptors (literal)
Abstract
  • Abstract--Endocannabinoids have emerged as a new class of lipid mediators, with manifold roles in the central nervous system and in the periphery. Several studies have identified 2-arachidonoyl-glycerol (2-AG) as a major endogenous agonist of cannabinoid receptors. Here, the chemical synthesis of 2-AG is reported, along with the synthesis of its tritium-labeled derivative. These unlabeled and radiolabeled compounds are suitable tools for unravelling some metabolic routes and biological activities of 2-AG in various cells and tissues. (literal)
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