Mating-related interactions share common features with anxiety in the mouse (Articolo in rivista)

Type
Label
  • Mating-related interactions share common features with anxiety in the mouse (Articolo in rivista) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Alternative label
  • Carola V; Scalera E; Brunamonti E; Gross C; D'Amato FR. (2008)
    Mating-related interactions share common features with anxiety in the mouse
    in Behavioural brain research
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Carola V; Scalera E; Brunamonti E; Gross C; D'Amato FR. (literal)
Pagina inizio
  • 185 (literal)
Pagina fine
  • 190 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 186 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Mouse Biology Unit, European Molecular Biology Laboratory (EMBL), Via Ramarini 32, 00015 Monterotondo, Italy CNR Institute of Neuroscience, Via del Fosso di Fiorano 64, 00137 Rome, Italy Department of Human Physiology and Pharmacology, University of Rome, \"La Sapienza\", P.le Aldo Moro 5, 00185 Rome, Italy (literal)
Titolo
  • Mating-related interactions share common features with anxiety in the mouse (literal)
Abstract
  • Anxiety is an important modulator of social behavior across species and parallel defects in anxiety and social interaction are frequently observed in mental illnesses such as autism and schizophrenia. The mouse is a powerful model organism to study the molecular genetic basis of these behaviors. Hereweanalyzed the relationship between social behavior and innate anxiety in C57BL/6 andBALB/c mice using a mating-related interaction (MRI) test in which a resident male was observed during exposure to a sexually receptive female. Unlike male-male encounters where social interaction is brief and tentative and aggressive behaviors are prominent, male-female encounters are characterized by a strong motivation for extensive social interaction with the potential for modulation by innate anxiety. We hypothesized that differences in innate avoidance behavior between mouse-inbred strains would contribute to mating-related social interaction strategies. Our observations showed that C57BL/6 and BALB/c males exhibited distinct approach strategies in the mating-related interaction test that correlated with specific features of anxiety as observed in the open field. These findings suggest that mating-related social approach behavior shares similar genetic determinants with non-social approach-avoidance behaviors. (literal)
Prodotto di
Autore CNR
Insieme di parole chiave

Incoming links:


Prodotto
Autore CNR di
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
Insieme di parole chiave di
data.CNR.it