Multislice multiecho T2* cardiac magnetic resonance for the detection of heterogeneous myocardial iron distribution in thalassaemia patients (Articolo in rivista)
- Type
- Articolo in rivista (Classe)
- Prodotto della ricerca (Classe)
- Label
- Multislice multiecho T2* cardiac magnetic resonance for the detection of heterogeneous myocardial iron distribution in thalassaemia patients (Articolo in rivista) (literal)
- Anno
- 2009-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1002/nbm.1382 (literal)
- Alternative label
- Positano, V (Positano, Vincenzo)[ 1,2 ] ; Pepe, A (Pepe, Alessia)[ 1,2 ] ; Santarelli, MF (Santarelli, Maria Filomena)[ 1,2 ] ; Ramazzotti, A (Ramazzotti, Anna)[ 1,2 ] ; Meloni, A (Meloni, Antonella)[ 1,2 ] ; De Marchi, D (De Marchi, Danielle)[ 1,2 ] ; Favilli, B (Favilli, Brunella)[ 1,2 ] ; Cracolici, E (Cracolici, Eliana)[ 3 ] ; Midiri, M (Midiri, Massimo)[ 3 ] ; Spasiano, A (Spasiano, Anna)[ 4 ] ; Lombardi, M (Lombardi, Massimo)[ 1,2 ] ; Landini, L (Landini, Luigi)[ 1,2,5 ] (2009)(literal)
Multislice multiecho T2* cardiac magnetic resonance for the detection of heterogeneous myocardial iron distribution in thalassaemia patients
in NMR in biomedicine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Positano, V (Positano, Vincenzo)[ 1,2 ] ; Pepe, A (Pepe, Alessia)[ 1,2 ] ; Santarelli, MF (Santarelli, Maria Filomena)[ 1,2 ] ; Ramazzotti, A (Ramazzotti, Anna)[ 1,2 ] ; Meloni, A (Meloni, Antonella)[ 1,2 ] ; De Marchi, D (De Marchi, Danielle)[ 1,2 ] ; Favilli, B (Favilli, Brunella)[ 1,2 ] ; Cracolici, E (Cracolici, Eliana)[ 3 ] ; Midiri, M (Midiri, Massimo)[ 3 ] ; Spasiano, A (Spasiano, Anna)[ 4 ] ; Lombardi, M (Lombardi, Massimo)[ 1,2 ] ; Landini, L (Landini, Luigi)[ 1,2,5 ] (literal)
- Pagina inizio
- 707 (literal)
- Pagina fine
- 715 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- 22 (literal)
- Rivista
- NMR in biomedicine (Rivista)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
- In: Nmr in Biomedicine, vol. 22 pp. 707 - 715. John Wiley & Sons, 2009. In: Nmr in Biomedicine, vol. 22 pp. 707 - 715. John Wiley & Sons, Ltd, 2009. (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
- 7 (literal)
- Note
- PubMe (literal)
- ISI Web of Science (WOS) (literal)
- Scopu (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- [ 1 ] Gabriele Monasterio Fdn, MRI Lab, I-56124 Pisa, Italy - [ 2 ] CNR, Inst Clin Physiol, I-56100 Pisa, Italy - [ 3 ] Univ Palermo, Dept Radiol, Palermo, Italy - [ 4 ] Cardarelli Hosp, Ctr Cura Microcitemie, Naples, Italy - [ 5 ] Univ Pisa, Dept Informat Engn, Pisa, Italy (literal)
- Titolo
- Multislice multiecho T2* cardiac magnetic resonance for the detection of heterogeneous myocardial iron distribution in thalassaemia patients (literal)
- Abstract
- The present study investigated myocardial T2* heterogeneity in thalassaemia major (TM) patients by cardiac magnetic resonance (CMR), to determine whether is related to inhomogeneous iron overload distribution. A total of 230 TM patients consecutively referred to our laboratory were studied retrospectively. Three short-axis views (basal, medium and apical) of the left ventricle (LV) were obtained by multislice multiecho T2* CMR. T2* segmental distribution was mapped on a 16-segment LV model. The level of heterogeneity of the T2* segmental distribution, evaluated by the coefficient of variation (CoV),was compared with that of a surrogate data set, to determinewhether the inhomogeneous segmental distribution of T2* could be generated by susceptibility artefacts. Susceptibility artefacts offer an explanation for the T2* heterogeneity observed in patientswithout iron overload. In subjectswith global T2* belowthe lower limit of the normal, T2* heterogeneity increased abruptly which could not be xplained by artefactual effects. Some segmental T2* values were below and others above the limit of normal threshold (20ms) in 104 (45%) TM patients. Among these patients, 74% showed a normal T2* global value. In conclusion, a true heterogeneity in the iron overload distribution may be present in TM patients. Heterogeneity seemingly appears in the borderline myocardial iron and stabilizes at moderate to severe iron burden. (literal)
- Prodotto di
- Istituto di fisiologia clinica (IFC) (Istituto)
- TECNOLOGIE BIOMEDICHE (ME.P06.028.001) (Modulo)
- Autore CNR
- LUIGI LANDINI (Unità di personale esterno)
- MARIA FILOMENA SANTARELLI (Persona)
- Insieme di parole chiave
Incoming links:
- Prodotto
- Istituto di fisiologia clinica (IFC) (Istituto)
- TECNOLOGIE BIOMEDICHE (ME.P06.028.001) (Modulo)
- Autore CNR di
- MARIA FILOMENA SANTARELLI (Persona)
- LUIGI LANDINI (Unità di personale esterno)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
- NMR in biomedicine (Rivista)
- Insieme di parole chiave di