http://www.cnr.it/ontology/cnr/individuo/prodotto/ID168805
Compatibilized polymer blends based on PDLLA and PCL for application in bioartificial liver (Articolo in rivista)
- Type
- Label
- Compatibilized polymer blends based on PDLLA and PCL for application in bioartificial liver (Articolo in rivista) (literal)
- Anno
- 2008-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1021/bm7013087 (literal)
- Alternative label
Calandrelli L.; Calarco A.; Laurienzo P.; Malinconico M.; Petillo O.; Peluso G. (2008)
Compatibilized polymer blends based on PDLLA and PCL for application in bioartificial liver
in Biomacromolecules; ACS, American chemical society, Washington, DC (Stati Uniti d'America)
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Calandrelli L.; Calarco A.; Laurienzo P.; Malinconico M.; Petillo O.; Peluso G. (literal)
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni
- N° citazioni: 8 (Fonte: Web of Science) (literal)
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- PubMe (literal)
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Institute of Polymers Chemistry and Technology, CNR, Via Campi Flegrei 34, 80078 Pozzuoli (Naples), Italy;
Institute of Protein Biochemistry, CNR, Via Pietro Castellino 111, 80131 Naples, Italy. (literal)
- Titolo
- Compatibilized polymer blends based on PDLLA and PCL for application in bioartificial liver (literal)
- Abstract
- Porous scaffolds for tissue engineering applications based on poly(D,L-lactide)/poly(epsilon-caprolactone) compatibilized blends are described. The addition of a third polymer, namely poly( d, l-lactide -co-caprolactone) copolymer, has a profound effect on morphological properties of the blends scaffolds. In fact, the copolymer acts as compatibilizing agent and reduces the dimension of the dispersed phase of an order of magnitude. Such effect is function of the polymer composition. The efficiency of scaffolds obtained with poly(d, l-lactide) based blends containing 30% by weight of poly(epsilon-caprolactone) as dispersed phase toward hepatocytes has been tested by several biological assays and we found that they are able to promote a perfect adhesion, proliferation and growth of cells. Moreover, the addition of the copolymer significantly improves the biomedical performance of the scaffold. (literal)
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