Localization and trafficking of fluorescently tagged ERK1 and ERK2 (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Localization and trafficking of fluorescently tagged ERK1 and ERK2 (Articolo in rivista) (literal)

Anno

• 2010-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1007/978-1-60761-795-2_17 (literal)

Alternative label

• Marchi M; Parra R; Costa M; Ratto GM (2010)
  Localization and trafficking of fluorescently tagged ERK1 and ERK2
  in Methods in molecular biology (Clifton N.J.); SPRINGER, 233 SPRING ST, NEW YORK, NY 10013 (Stati Uniti d'America)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Marchi M; Parra R; Costa M; Ratto GM (literal)

Pagina inizio

• 287 (literal)

Pagina fine

• 301 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.springerlink.com/content/n58817835668210q/?MUD=MP (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#titoloVolume

• MAP KINASE SIGNALING PROTOCOLS (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 661 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#volumeInCollana

• 661 (literal)

Rivista

• Methods in molecular biology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 15 (literal)

Note

• PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• istituto Nanoscienze Scuola Normale Superiore (literal)

Titolo

• Localization and trafficking of fluorescently tagged ERK1 and ERK2 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autoriVolume

• Marchi M; Parra R; Costa M; Ratto GM (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#curatoriVolume

• Seger (literal)

Abstract

• The action of ERK1 and ERK2 activity on the nuclear substrates requires crossing the nuclear envelope and the localization of phospho-ERK into the nucleus. The nucleo-cytoplasmic trafficking of ERK is therefore crucial for the correct functioning of the pathway. Indeed, this step is necessary for the correct control of gene expression by growth-factors, for morphological transformation of fibroblasts and for neurite extension in PC12. Furthermore, disruption of ERK2 localization in the nucleus severely affects the transduction of ERK2 signaling. This process has now been observed and quantitatively measured by expressing fluorescently tagged ERK1 and ERK2. These experiments provide important insight on the operation of these signaling modules and have revealed an hitherto unknown functional difference between ERK1 and ERK2. (literal)

Editore

• SPRINGER, 233 SPRING ST (Editore)

Autore CNR

• GIAN MICHELE RATTO (Persona)
• MARIO COSTA (Unità di personale interno)

Incoming links:

Autore CNR di

• MARIO COSTA (Unità di personale interno)
• GIAN MICHELE RATTO (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Methods in molecular biology (Rivista)

Editore di

• SPRINGER, 233 SPRING ST (Editore)