http://www.cnr.it/ontology/cnr/individuo/prodotto/ID168401
Efficient synthesis of polyoxygenated flavones from naturally occurring flavanones (Articolo in rivista)
- Type
- Label
- Efficient synthesis of polyoxygenated flavones from naturally occurring flavanones (Articolo in rivista) (literal)
- Anno
- 2007-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1211/jpp.59.12.0012 (literal)
- Alternative label
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Bovicelli P.; D'Angelo V.; Collalto D.; Verzina A.; D'Antona N.; Lambusta D. (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni
- Selected and revised paper Conference: Workshop on Chemistry and Biology of Antioxidants Location: Rome, ITALY Date: JUL, 2007. (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
- Note
- ISI Web of Science (WOS) (literal)
- Scopu (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- C.N.R. Instituto di Chimica
Biomolecolare, Sezione di Roma,
c/o Dipartimento di Chimica,
Università di Roma 'La Sapienza',
p.le A. Moro 5, I-00185 Roma,
Italy; C.N.R. Istituto di Chimica
Biomolecolare, Sezione di
Catania, Via del Santuario 110,
I-95028 Valverde CT, Italy (literal)
- Titolo
- Efficient synthesis of polyoxygenated flavones from naturally occurring flavanones (literal)
- Abstract
- Flavonoids are constituents of the human diet (they are present in many beverages and food), and in
organisms they are responsible for several biological functions, including that of antioxidant. Because
of the increasing interest in these molecules, methods for their synthesis and structural modification
are of great importance; studies on the biological activities of many of these compounds are insufficient
because of their scarcity and/or high cost. We have developed an expeditious synthesis of polyoxygenated
flavones, starting from available and inexpensive flavanones, using a bromination-
methoxylation procedure. A series of flavonoids that are not otherwise accessible can be prepared
using this method. As an example, 3?-demethoxysudachitin, a limited flavone possessing antimicrobial
activity against methicillin-resistant Staphylococcus aureus and Helicobacter pylori and acting as a 2,2-
diphenyl-1-picrylhydrazyl (DPPH) scavenger, was prepared in fairly satisfactory yield. (literal)
- Prodotto di
- Autore CNR
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