Exposure to 900 MHz radiofrequency radiation induces Caspase 3 activation in proliferating human lymphocytes (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Exposure to 900 MHz radiofrequency radiation induces Caspase 3 activation in proliferating human lymphocytes (Articolo in rivista) (literal)

Anno

• 2008-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1667/RR1098.1 (literal)

Alternative label

• Palumbo R; Brescia F; Capasso D; Sannino A; Sarti M; Capri M; Grassilli E; Scarfi MR; (2008)
  Exposure to 900 MHz radiofrequency radiation induces Caspase 3 activation in proliferating human lymphocytes
  in Radiation research
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Palumbo R; Brescia F; Capasso D; Sannino A; Sarti M; Capri M; Grassilli E; Scarfi MR; (literal)

Pagina inizio

• 327 (literal)

Pagina fine

• 334 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.bioone.org/doi/abs/10.1667/RR1098.1 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 170 (literal)

Rivista

• Radiation research (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto

• Pubblicazione su rivista internazionale (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• CNR-Institute of Biostructure and Bioimaging, Naples, Italy CNR-Institute for Electromagnetic Sensing of Environment, Naples, Italy; Department of Biological Sciences, University of Naples Federico II, Naples, Italy; CNR-Institute for Electromagnetic Sensing of Environment, Naples, Italy; CNR-Institute for Electromagnetic Sensing of Environment, Naples, Italy; Department of Experimental Pathology, University of Bologna, Italy; Department of Surgical Sciences, School of Medicine, University of Milano-Bicocca, Italy CNR-Institute for Electromagnetic Sensing of Environment, Naples, Italy; (literal)

Titolo

• Exposure to 900 MHz radiofrequency radiation induces Caspase 3 activation in proliferating human lymphocytes (literal)

Abstract

• In this study, the induction of apoptosis after exposure to 900 MHz radiofrequency radiation (GSM signal) was investigated by assessing caspase 3 activation in exponentially growing Jurkat cells and in quiescent and proliferating human peripheral blood lymphocytes (PBLs). The exposure was carried out at an average specific absorption rate of 1.35 W/kg in a dual wire patch cell exposure system where the temperature of cell cultures was accurately controlled. After 1 h exposure to the radiofrequency field, a slight but statistically significant increase in caspase 3 activity, measured 6 h after exposure, was observed in Jurkat cells (32.4%) and in proliferating human PBLs (22%). In contrast, no effect was detected in quiescent human PBLs. In the same experimental conditions, apoptosis was also evaluated in Jurkat cells by Western blot analysis and in both cell types by flow cytometry. To evaluate late effects due to caspase 3 activity, flow cytometry was also employed to assess apoptosis and viability 24 h after radiofrequency-radiation exposure in both cell types. Neither the former nor the latter was affected. Since in recent years it has been reported that caspases are also involved in processes other than apoptosis, additional cell cycle studies were carried out on proliferating T cells exposed to radiofrequency radiation; however, we found no differences between sham-exposed and exposed cultures. Further studies are warranted to investigate the biological significance of our findings of a dose-response increase in caspase 3 activity after exposure to radiofrequency radiation. (literal)

Prodotto di

• Institute of biostructure and bioimaging (IBB) (Istituto)
• effetti biologici dei campi elettromagnetici (INT.P01.006.002) (Modulo)
• Sviluppo di repertori molecolari per l'identificazione di antagonisti di interazioni proteina-proteina e proteina-ligando (PM.P01.005.001) (Modulo)
• Istituto per il rilevamento elettromagnetico dell'ambiente (IREA) (Istituto)

Autore CNR

• FRANCESCA BRESCIA (Persona)
• ROSANNA PALUMBO (Unità di personale interno)
• MAURIZIO SARTI (Unità di personale interno)
• ANNA SANNINO (Persona)
• MARIA ROSARIA SCARFI' (Unità di personale interno)

Incoming links:

Autore CNR di

• MAURIZIO SARTI (Unità di personale interno)
• MARIA ROSARIA SCARFI' (Unità di personale interno)
• ROSANNA PALUMBO (Unità di personale interno)
• ANNA SANNINO (Persona)
• FRANCESCA BRESCIA (Persona)

Prodotto

• Institute of biostructure and bioimaging (IBB) (Istituto)
• Istituto per il rilevamento elettromagnetico dell'ambiente (IREA) (Istituto)
• Sviluppo di repertori molecolari per l'identificazione di antagonisti di interazioni proteina-proteina e proteina-ligando (PM.P01.005.001) (Modulo)
• effetti biologici dei campi elettromagnetici (INT.P01.006.002) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Radiation research (Rivista)