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Late reproduction behaviour in Sardinia: spatial analysis suggests local aptitude towards reproductive longevity (Articolo in rivista)
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- Late reproduction behaviour in Sardinia: spatial analysis suggests local aptitude towards reproductive longevity (Articolo in rivista) (literal)
- Anno
- 2009-01-01T00:00:00+01:00 (literal)
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Paola Astolfi; Graziella Caselli; Ornella Fiorani; Rosa M. Lipsi; Antonella Lisa; Stefania Tentoni (2009)
Late reproduction behaviour in Sardinia: spatial analysis suggests local aptitude towards reproductive longevity
in Evolution and human behavior; Elsevier Science Inc., New York (Stati Uniti d'America)
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- Paola Astolfi; Graziella Caselli; Ornella Fiorani; Rosa M. Lipsi; Antonella Lisa; Stefania Tentoni (literal)
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- Department of Genetics and Microbiology, University of Pavia, 27100 Pavia, Italy;
Department of Demographic Sciences, University of Rome La Sapienza, 00161 Rome, Italy;
IGM-CNR, 27100 Pavia, Italy;
IMATI-CNR, Pavia, 27100 Italy (literal)
- Titolo
- Late reproduction behaviour in Sardinia: spatial analysis suggests local aptitude towards reproductive longevity (literal)
- Abstract
- Evolution in human life-history traits is influenced by environmental factors and, when genetic components underlie the relations, by micro-evolutionary forces. Age at reproduction is largely influenced by the familial cultural context and socioeconomic level, besides the maternal well-being and genetic background. The Sardinian population is characterized by historico-geographical isolation and differentiates from Italian mainland and other European populations in bio-demographic and cultural characteristics, among which the tendency to delay maternity persisting through generations. In our study, we investigated whether, in Sardinia, areas of \"reproductive longevity\" exist, where a higher-than-average incidence of late maternities combines with a lower-than-average cost in terms of perinatal death. Data from the Italian
Central Institute of Statistics regard all 1980-1996 Sardinian births. Using spatial analysis of late maternity (proportion of babies born to mothers aged >=35 years) and associated perinatal mortality (proportion of babies stillborn and dead within 0-6 days born to mothers aged >=35 years), we aimed at singling out areas where the indicators run high and low, respectively. The perinatal mortality cost associated with the advanced maternal age [odds ratios (95% CI)] was evaluated through multiple logistic regression models. We identified central inland excess areas qualified by higher incidence of late maternities (27% vs. 22% in nonexcess area) and lower cost in perinatal mortality [OR=1.38 (1.04-1.84) vs. OR=1.74 (1.55-1.96) in nonexcess area]. In these \"reproductive longevity\" areas, the inbreeding coefficient was 3.7-fold
higher than in the nonexcess areas, suggesting possible population homozygosity in genetic factors affecting the trait. Further and deeper
investigations on biological and environmental determinants could focus on these target areas. (literal)
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