http://www.cnr.it/ontology/cnr/individuo/prodotto/ID167838

High performance workflow implementation for protein surface characterization using grid technology (Articolo in rivista)

Type

Prodotto della ricerca (Classe)
Articolo in rivista (Classe)

Label

High performance workflow implementation for protein surface characterization using grid technology (Articolo in rivista) (literal)

Anno

2005-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

10.1186/1471-2105-6-S4-S19 (literal)

Alternative label

Merelli I.; Morra G.; D'Agostino D.; Clematis A.; Milanesi L. (2005)
High performance workflow implementation for protein surface characterization using grid technology
in BMC bioinformatics; Biomed Central Ltd., London (Regno Unito)
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Merelli I.; Morra G.; D'Agostino D.; Clematis A.; Milanesi L. (literal)

Pagina inizio

S19-1 (literal)

Pagina fine

S19-8 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni

It publishes selected research, proceedings and collections of thematic reviews from Italian Society of Bioinformatics (BITS): Annual Meeting 2005 Milan, Italy 17-19 March 2005 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

http://www.biomedcentral.com/1471-2105/6/S4/S19 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

6 (literal)

Rivista

BMC bioinformatics (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

Supplement-4 (literal)

Note

ISI Web of Science (WOS) (literal)
Scopu (literal)
PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

Merelli I.; Morra G.; Milanesi L. Istituto di Tecnologie Biomediche (ITB CNR), via F.lli Cervi, Segrate (Milano), Italy and D'Agostino D.; Clematis A. Istituto di Matematica Applicata e Tecnologie Informatiche (IMATI CNR), via de Marini, Genova, Italy (literal)

Titolo

High performance workflow implementation for protein surface characterization using grid technology (literal)

Abstract

Background This study concerns the development of a high performance workflow that, using grid technology, correlates different kinds of Bioinformatics data, starting from the base pairs of the nucleotide sequence to the exposed residues of the protein surface. The implementation of this workflow is based on the Italian Grid.it project infrastructure, that is a network of several computational resources and storage facilities distributed at different grid sites. Methods Workflows are very common in Bioinformatics because they allow to process large quantities of data by delegating the management of resources to the information streaming. Grid technology optimizes the computational load during the different workflow steps, dividing the more expensive tasks into a set of small jobs. Results Grid technology allows efficient database management, a crucial problem for obtaining good results in Bioinformatics applications. The proposed workflow is implemented to integrate huge amounts of data and the results themselves must be stored into a relational database, which results as the added value to the global knowledge. Conclusion A web interface has been developed to make this technology accessible to grid users. Once the workflow has started, by means of the simplified interface, it is possible to follow all the different steps throughout the data processing. Eventually, when the workflow has been terminated, the different features of the protein, like the amino acids exposed on the protein surface, can be compared with the data present in the output database. (literal)

Editore