Boron analysis and boron imaging in biological materials for Boron Neutron Capture Therapy (BNCT) (Articolo in rivista)

Type
Label
  • Boron analysis and boron imaging in biological materials for Boron Neutron Capture Therapy (BNCT) (Articolo in rivista) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.critrevonc.2008.03.004 (literal)
Alternative label
  • Wittig A; Michel J; Moss RL; Stecher-Rasmussen F; Arlinghaus HF; Bendel P; Mauri PL; Altieri S; Hilger R; Salvadori PA; Menichetti L; Zamenhof R; Sauerwein WA. (2008)
    Boron analysis and boron imaging in biological materials for Boron Neutron Capture Therapy (BNCT)
    in Critical reviews in oncology/hematology
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Wittig A; Michel J; Moss RL; Stecher-Rasmussen F; Arlinghaus HF; Bendel P; Mauri PL; Altieri S; Hilger R; Salvadori PA; Menichetti L; Zamenhof R; Sauerwein WA. (literal)
Pagina inizio
  • 66 (literal)
Pagina fine
  • 90 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 68 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 24 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 1 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Department of Radiation Oncology, University Duisburg-Essen, University Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany Laboratoire de Microscopie Electronique Analytique, INSERM ERM 0203, Université de Reims Champagne-Ardenne, Reims, France HFR Unit, Institute for Energy, Joint Research Centre, Petten, Netherlands NCT Physics, Alkmaar, Netherlands Physikalisches Institut, Westfälische Wilhelms-Universität Münster, Münster, Germany Chemical Research Support Department, The Weizmann Institute of Science, Rehovot, Israel Institute for Biomedical Technologies, Proteomic and Metabolic Unit, Segrate, Milan, Italy Department of Nuclear and Theoretical Physics, University of Pavia, National Institute, Pavia, Italy Department of Medical Oncology, University Duisburg, University Hospital Essen, Essen, Germany C.N.R. Institute of Clinical Physiology, Pisa, Italy Midwest Proton Radiotherapy Institute, Department of Physics, Indiana University, Bloomington, IN, United States (literal)
Titolo
  • Boron analysis and boron imaging in biological materials for Boron Neutron Capture Therapy (BNCT) (literal)
Abstract
  • Boron Neutron Capture Therapy (BNCT) is based on the ability of the stable isotope 10B to capture neutrons, which leads to a nuclear reaction producing an alpha- and a 7Li-particle, both having a high biological effectiveness and a very short range in tissue, being limited to approximately one cell diameter. This opens the possibility for a highly selective cancer therapy. BNCT strongly depends on the selective uptake of 10B in tumor cells and on its distribution inside the cells. The chemical properties of boron and the need to discriminate different isotopes make the investigation of the concentration and distribution of 10B a challenging task. The most advanced techniques to measure and image boron are described, both invasive and non-invasive. The most promising approach for further investigation will be the complementary use of the different techniques to obtain the information that is mandatory for the future of this innovative treatment modality. © 2008 Elsevier Ireland Ltd. All rights reserved. (literal)
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