“Hollow-fiber enzyme reactor operating under nonisothermal conditions” (Articolo in rivista)

Type
Label
  • “Hollow-fiber enzyme reactor operating under nonisothermal conditions” (Articolo in rivista) (literal)
Anno
  • 2004-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1021/bp034197l (literal)
Alternative label
  • Diano N.; Grano V.; Rossi S.; Bencivenga U.; Portaccio M.; Amato U.; Carfora F.; Lepore M.; Gaeta F.S.; Mita D.G. (2004)
    “Hollow-fiber enzyme reactor operating under nonisothermal conditions”
    in Biotechnology progress (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Diano N.; Grano V.; Rossi S.; Bencivenga U.; Portaccio M.; Amato U.; Carfora F.; Lepore M.; Gaeta F.S.; Mita D.G. (literal)
Pagina inizio
  • 457 (literal)
Pagina fine
  • 466 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 20 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 2 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto
  • PUBBLICAZIONE (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Institute of Genetics and Biophysics \"A. Buzzati Traverso\" of CNR, Via G. Marconi 12, 80125 Naples, Italy, Dipartimento di Medicina Sperimentale, II Universita` di Napoli, Via S. M. di Costantinopoli 16, 80138 Naples, Italy, and Istituto per le Applicazioni del Calcolo \"Mauro Picone\"-Sezione di Napoli, Via P. Castellino 111, 80127 Naples, Italy (literal)
Titolo
  • “Hollow-fiber enzyme reactor operating under nonisothermal conditions” (literal)
Abstract
  • A hollow-fiber enzyme reactor, operating under isothermal and nonisothermal conditions, was built employing a polypropylene hollow fiber onto which â-galactosidase was immobilized. Hexamethylenediamine and glutaraldehyde were used as spacer and coupling agent, respectively. Glucose production was studied as a function of temperature, substrate concentration, and size of the transmembrane temperature gradient. The actual average temperature differences across the polypropylene fiber, to which reference was done to evaluate the effect of the nonisothermal conditions, were calculated by means of a mathematical approach, which made it possible to know, using computer simulation, the radial and axial temperature profiles inside the bioreactor and across the membrane. Percent activity increases, proportional to the size of the temperature gradients, were found when the enzyme activities under nonisothermal conditions were compared to those measured under comparable isothermal conditions. Percent reductions of the production times, proportional to the applied temperature gradients, were also calculated. The advantage of employing nonisothermal bioreactors in biotechnological industrial process was discussed. (literal)
Prodotto di
Autore CNR

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