Womersley Number-Based Estimates of Blood Flow Rate in Doppler Analysis: In Vivo Validation by Means of Phase-Contrast MRI (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Womersley Number-Based Estimates of Blood Flow Rate in Doppler Analysis: In Vivo Validation by Means of Phase-Contrast MRI (Articolo in rivista) (literal)

Anno

• 2010-01-01T00:00:00+01:00 (literal)

Alternative label

• Ponzini R.; Vergara C.; Rizzo G.; Veneziani A.; Roghi A.; Vanzulli A.; Parodi O.; Redaelli A. (2010)
  Womersley Number-Based Estimates of Blood Flow Rate in Doppler Analysis: In Vivo Validation by Means of Phase-Contrast MRI
  in IEEE transactions on biomedical engineering (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Ponzini R.; Vergara C.; Rizzo G.; Veneziani A.; Roghi A.; Vanzulli A.; Parodi O.; Redaelli A. (literal)

Pagina inizio

• 1807 (literal)

Pagina fine

• 1815 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 57 (literal)

Rivista

• IEEE transactions on biomedical engineering (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• Corresponding author: R. Ponzini (e-mail: ponzini@cilea.it) IF 2010: 1.782 In: IEEE Transaction on biomedical engineering, vol. 57 pp. 1807 - 1815. EMB, 2010. (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1. High Performance Computing Division, Consorzio Interuniversitario Lombardo per l’Elaborazione Automatica, Segrate (MI). 2. Department of Information Engineering and Mathematical Methods, Università degli Studi, Bergamo. 3. CNR-IBFM, Segrate (MI). 4. Department of Mathematics and Computer Science, and the Wallace H Coulter Department of Biomedical Engineering at Georgia Technical and Emory, Emory University, Atlanta (USA). 5. Department of Cardiology and Cardiac Surgery, Niguarda Ca’ Granda Hospital, Milano. 6. Ca’ Granda Niguarda Hospital, Milano. 7. CNR-IFC, Pisa. 8. Department of Bioengineering, Politecnico di Milano. (literal)

Titolo

• Womersley Number-Based Estimates of Blood Flow Rate in Doppler Analysis: In Vivo Validation by Means of Phase-Contrast MRI (literal)

Abstract

• A common clinical practice during single-point Doppler analysis is to measure the centerline maximum velocity and to recover the time-averaged flow rate by exploiting an assumption on the shape of velocity profile (a priori formula), either a parabolic or a flat one. In a previous study, we proposed a new formula valid for the peak instant linking the maximum velocity and the flow rate by including a well-established dimensionless fluid-dynamics parameter (theWomersley number), in order to account for the hemodynamics conditions (Womersley number-based formula). Several in silico tests confirmed the reliability of the new formula. Nevertheless, an in vivo confirmation is missing limiting the clinical applicability of the formula. An experimental in vivo protocol using cine phase-contrast MRI (2-D PCMRI) technique has been designed and applied to ten healthy young volunteers in three different arterial districts: the abdominal aorta, the common carotid artery, and the brachial artery. Each PCMRI dataset has been used twice: 1) to compute the value of the blood flow rate used as a gold standard and 2) to estimate the flow rate by measuring directly the maximum velocity and the diameter (i.e., emulating the intravascular Doppler data acquisition) and by applying to these data the a priori and the Womersley number-based formulae. All the in vivo results have confirmed that the Womersley numberbased formula provides better estimates of the flow rate at the peak instant with respect to the a priori formula. More precisely mean performances of the Womersley number-based formula are about three times better than the a priori results in the abdominal aorta, five times better in the common carotid artery, and two times better in the brachial artery. (literal)

Prodotto di

• Meccanismi molecolari e biologici (ME.P05.018.002) (Modulo)
• Istituto di fisiologia clinica (IFC) (Istituto)
• Institute of molecular bioimaging and physiology (IBFM) (Istituto)
• Attività fisica e risposta cardiocircolatoria nella patologia dismetabolica e cardiovascolare (ME.P01.002.006) (Modulo)

Autore CNR

• OBERDAN PARODI (Persona)
• GIOVANNA RIZZO (Persona)

Insieme di parole chiave

• Keywords of "Womersley Number-Based Estimates of Blood Flow Rate in Doppler Analysis: In Vivo Validation by Means of Phase-Contrast MRI" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• GIOVANNA RIZZO (Persona)
• OBERDAN PARODI (Persona)

Prodotto

• Istituto di fisiologia clinica (IFC) (Istituto)
• Institute of molecular bioimaging and physiology (IBFM) (Istituto)
• Attività fisica e risposta cardiocircolatoria nella patologia dismetabolica e cardiovascolare (ME.P01.002.006) (Modulo)
• Meccanismi molecolari e biologici (ME.P05.018.002) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• IEEE transactions on biomedical engineering (Rivista)

Insieme di parole chiave di

• Keywords of "Womersley Number-Based Estimates of Blood Flow Rate in Doppler Analysis: In Vivo Validation by Means of Phase-Contrast MRI" (Insieme di parole chiave)