http://www.cnr.it/ontology/cnr/individuo/prodotto/ID166915
Phenotypic and genotypic characteristics of new euploid-diploid lymphoblastoid B cell lines EBV+, normal human bone marrow derived, spontaneously overgrown in vitro. (Articolo in rivista)
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- Label
- Phenotypic and genotypic characteristics of new euploid-diploid lymphoblastoid B cell lines EBV+, normal human bone marrow derived, spontaneously overgrown in vitro. (Articolo in rivista) (literal)
- Anno
- 2005-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1016/j.jviromet.2005.01.029 (literal)
- Alternative label
Bertolini L.1; Aebischer M.L.2; Ameglio F.3; Angeloni A.4; Delaroche I.5; Faggioni A.6; Fruscalzo A.7; Gorini G.8; Serafino A.9; Starace G.10; Tabilio A.11 (2005)
Phenotypic and genotypic characteristics of new euploid-diploid lymphoblastoid B cell lines EBV+, normal human bone marrow derived, spontaneously overgrown in vitro.
in Journal of virological methods
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Bertolini L.1; Aebischer M.L.2; Ameglio F.3; Angeloni A.4; Delaroche I.5; Faggioni A.6; Fruscalzo A.7; Gorini G.8; Serafino A.9; Starace G.10; Tabilio A.11 (literal)
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- Impact Factor = 1.886 (literal)
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- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- 1,10 = Istituto di Neurobiologia e Medicina Molecolare, CNR, Via del Fosso del Cavaliere, 100, 00133 Rome, Italy;
2,5 = Laboratorio Centrale, Croce Rossa Italiana, CRI, Rome, Italy;
3 = Laboratory of Clinical Pathology, S. Giovanni Calibita Hospital, Fatebenefratelli/AFAR Foundation, Rome, Italy;
4,6 = Dipartimento di Medicina Sperimentale e Patologia, Università La Sapienza, Rome, Italy;
7 = Istituto di Biologia e Patologia Molecolari, CNR, Rome, Italy;
8 = Dipartimento Ambiente, ENEA, Casaccia, Rome, Italy;
9 = Area di Ricerca di Roma Tor Vergata, CNR, Rome, Italy;
11 = Dip. di Medicina Clinica e Sperimentale, Ematologia ed Immunologia Clinica, Università di Perugia, Perugia, Italy. (literal)
- Titolo
- Phenotypic and genotypic characteristics of new euploid-diploid lymphoblastoid B cell lines EBV+, normal human bone marrow derived, spontaneously overgrown in vitro. (literal)
- Abstract
- The present study describes the phenotypic and genotypic features of seven individual growth transformed, euploiddiploid EBV+ human B cell lines arisen spontaneously in vitro.
The lines, obtained under general and standard culture conditions (un-manipulated), from seven individual bone marrow samples of 18 healthy young adults, Caucasian, of both sexes, display many traits of normal B cells and represent a mixture of EBV infected latently (latency type III) and producer cells (516% VCA+ by immunofluorescence) releasing seven individual different viral strains [Fruscalzo et al., 2001. DNA sequence heterogeneity within the Epstein-Barr virus family of repeats in the latent origin of replication. Gene 265, 165173] similar to the B95-8 genotype as shown by results of Southern blot of BamHI-digested DNA fragment.
These tests were planned to characterize more fully this panel of new bone marrow cell lines sharing normal B cell traits. (literal)
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