Phenotypic and genotypic characteristics of new euploid-diploid lymphoblastoid B cell lines EBV+, normal human bone marrow derived, spontaneously overgrown in vitro. (Articolo in rivista)

Type
Label
  • Phenotypic and genotypic characteristics of new euploid-diploid lymphoblastoid B cell lines EBV+, normal human bone marrow derived, spontaneously overgrown in vitro. (Articolo in rivista) (literal)
Anno
  • 2005-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.jviromet.2005.01.029 (literal)
Alternative label
  • Bertolini L.1; Aebischer M.L.2; Ameglio F.3; Angeloni A.4; Delaroche I.5; Faggioni A.6; Fruscalzo A.7; Gorini G.8; Serafino A.9; Starace G.10; Tabilio A.11 (2005)
    Phenotypic and genotypic characteristics of new euploid-diploid lymphoblastoid B cell lines EBV+, normal human bone marrow derived, spontaneously overgrown in vitro.
    in Journal of virological methods
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Bertolini L.1; Aebischer M.L.2; Ameglio F.3; Angeloni A.4; Delaroche I.5; Faggioni A.6; Fruscalzo A.7; Gorini G.8; Serafino A.9; Starace G.10; Tabilio A.11 (literal)
Pagina inizio
  • 91 (literal)
Pagina fine
  • 100 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni
  • Impact Factor = 1.886 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 126 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 1-2 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1,10 = Istituto di Neurobiologia e Medicina Molecolare, CNR, Via del Fosso del Cavaliere, 100, 00133 Rome, Italy; 2,5 = Laboratorio Centrale, Croce Rossa Italiana, CRI, Rome, Italy; 3 = Laboratory of Clinical Pathology, S. Giovanni Calibita Hospital, Fatebenefratelli/AFAR Foundation, Rome, Italy; 4,6 = Dipartimento di Medicina Sperimentale e Patologia, Università “La Sapienza”, Rome, Italy; 7 = Istituto di Biologia e Patologia Molecolari, CNR, Rome, Italy; 8 = Dipartimento Ambiente, ENEA, Casaccia, Rome, Italy; 9 = Area di Ricerca di Roma Tor Vergata, CNR, Rome, Italy; 11 = Dip. di Medicina Clinica e Sperimentale, Ematologia ed Immunologia Clinica, Università di Perugia, Perugia, Italy. (literal)
Titolo
  • Phenotypic and genotypic characteristics of new euploid-diploid lymphoblastoid B cell lines EBV+, normal human bone marrow derived, spontaneously overgrown in vitro. (literal)
Abstract
  • The present study describes the phenotypic and genotypic features of seven individual growth transformed, euploid–diploid EBV+ human B cell lines arisen spontaneously in vitro. The lines, obtained under general and standard culture conditions (un-manipulated), from seven individual bone marrow samples of 18 healthy young adults, Caucasian, of both sexes, display many traits of normal B cells and represent a mixture of EBV infected latently (latency type III) and producer cells (5–16% VCA+ by immunofluorescence) releasing seven individual different viral strains [Fruscalzo et al., 2001. DNA sequence heterogeneity within the Epstein-Barr virus family of repeats in the latent origin of replication. Gene 265, 165–173] similar to the B95-8 genotype as shown by results of Southern blot of BamHI-digested DNA fragment. These tests were planned to characterize more fully this panel of new bone marrow cell lines sharing normal B cell traits. (literal)
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