http://www.cnr.it/ontology/cnr/individuo/prodotto/ID15955
High level synthesis of levan by a novel Halomonas species growing on defined media. (Articolo in rivista)
- Type
- Label
- High level synthesis of levan by a novel Halomonas species growing on defined media. (Articolo in rivista) (literal)
- Anno
- 2009-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1016/j.carbpol.2009.05.031 (literal)
- Alternative label
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Poli A.; Kazak H.; Gurleyendag B.; Tommonaro G.; Pieretti G.; Toksoy Oner E.; Nicolaus B. (literal)
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- Pagina fine
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- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
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- Scopu (literal)
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Institute of Biomolecular Chemistry (ICB), Consiglio Nazionale delle Ricerche C.N.R., Via Campi Flegrei 34, 80078 Pozzuoli (Na), Italy
Department of Bioengineering, Marmara University, Goztepe 34722, Istanbul, Turkey
Department of Chemistry, Marmara University, Goztepe 34722, Istanbul, Turkey
Department of Organic Chemistry and Biochemistry, Università Federico II, Via Cinthia 4, 80126 Napoli, Italy (literal)
- Titolo
- High level synthesis of levan by a novel Halomonas species growing on defined media. (literal)
- Abstract
- A novel halophilic isolate from soil samples taken from Çamalt? Saltern area in Turkey, Halomonas sp.
AAD6 (JCM 15723) strain, was found to produce high levels of exopolysaccharides (EPS), in the presence
of sucrose in defined media, by flasks and bioreactor condition yielded 1.073 g L-1 and 1.844 g L-1,
respectively. Sugar analysis, methylation studies and NMR analysis of EPS indicated the repeating unit
of this polysaccharide was composed of beta-(2,6)-D-fructofuranosyl residues. Hence with this work, Halomonas sp. has been described as a levan producer microorganism for the first time. Biocompatibility studies showed this EPS did not affect cellular viability and proliferation of osteoblasts and murine
macrophages. The protective effect of the polymer against the toxic activity of avarol implied its additional
use as an anti-cytotoxic agent. Halomonas sp. AAD6 could represent an alternative cheap source
of levan polymer when grown on defined media hypothesizing its larger employment in industrial application
being non pathogenic microorganism. (literal)
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