http://www.cnr.it/ontology/cnr/individuo/prodotto/ID15525
Structure and absolute stereochemistry of syphonoside, a unique macrocyclic glycoterpenoid from marine organisms. (Articolo in rivista)
- Type
- Label
- Structure and absolute stereochemistry of syphonoside, a unique macrocyclic glycoterpenoid from marine organisms. (Articolo in rivista) (literal)
- Anno
- 2007-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1021/jo0704917 (literal)
- Alternative label
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Gavagnin M.; Carbone M.; Amodeo P.; Mollo E.; Vitale R.M.; Roussis V.; Cimino G. (literal)
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- Scopu (literal)
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Istituto di Chimica Biomolecolare, CNR, Via Campi Flegrei 34, 80078 Pozzuoli (Naples), Italy, Istituto di Biostrutture e Bioimmagini, CNR, Via Mezzocannone 16, 80134 Naples, Italy, and Department of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy, UniVersity of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece. (literal)
- Titolo
- Structure and absolute stereochemistry of syphonoside, a unique macrocyclic glycoterpenoid from marine organisms. (literal)
- Abstract
- The glycoterpenoid syphonoside (1) is the main secondary metabolite of both the marine mollusk Syphonota geographica and the sea-grass Halophila stipulacea, two Indo-Pacific species migrated to the Mediterranean Sea through the Suez Canal. The structure and the absolute stereochemistry of 1, which displays unique structural features, has been accomplished by using a combination of spectroscopic techniques, degradation reactions, and conformational analysis methods. Compound 1 was able to inhibit high density induced apoptosis in a number of human and murine carcinoma cell lines. (literal)
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