Composti farmaceutici Diazabicyclic compounds as opioid receptor agonists (Brevetto)

Type
Label
  • Composti farmaceutici Diazabicyclic compounds as opioid receptor agonists (Brevetto) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Alternative label
  • Lazzari P., Loriga G., Ruiu S., Manca I., Pani L., Pinna G.A. (2008)
    Composti farmaceutici Diazabicyclic compounds as opioid receptor agonists
    (literal)
Titolo
  • Composti farmaceutici Diazabicyclic compounds as opioid receptor agonists (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Lazzari P., Loriga G., Ruiu S., Manca I., Pani L., Pinna G.A. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni
  • estensione brevetto europeo EP2149575 consultabile su http://worldwide.espacenet.com/publicationDetails/biblio?CC=IT&KC=A1&ND=3&FT=D&DB=EPODOC&NR=MI20081426A1&bcId=2&return=true&date=20100201&locale=en_EP (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#proprieta
  • Neuroscienze Pharmaness (literal)
Http://www.cnr.it/ontology/cnr/brevetti.owl#tipoDiBrevetto
  • Nazionale (literal)
Numero brevetto
  • MI2008A001426 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto
  • Nuovi composti oppioidi selettivi per i recettori mu (literal)
Anno di deposito
  • 2008 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Neuroscienze PharmaNess Parco scientifico e tecnologico della Sardegna (Pula, CA) UNIVERSITA' DEGLI STUDI DI SASSARI Piazza Università 21, I-07100 Sassari (literal)
Titolo
  • Composti farmaceutici Diazabicyclic compounds as opioid receptor agonists (literal)
Abstract
  • Nonane and decane diazabicyclic derivatives having homopiperazine as main ring, having affinity for the opioidergic [mu] and/or ' and/or k receptors and/or for all their receptorial subclasses, with central and/or peripheral activity, having formula (I), the isomeric forms and their mixtures included, wherein one or more atoms are in the corresponding isotopic forms: wherein: - n is an integer equal to 1 or 2; - one of the substituents R and R 1 of the nitrogen atoms of the diazabicyclic ring is a -C(O)-R B group, wherein R B is a C 1 -C 10 alkyl group, linear or branched when possible, - the other remained substituent of R and R 1 has the meanings reported in the description (literal)
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