http://www.cnr.it/ontology/cnr/individuo/prodotto/ID144275
Extremely-low frequency magnetic field modulates differentiation and maturation of human and rat primary and multipotent stem cells. (Contributo in volume (capitolo o saggio))
- Type
- Label
- Extremely-low frequency magnetic field modulates differentiation and maturation of human and rat primary and multipotent stem cells. (Contributo in volume (capitolo o saggio)) (literal)
- Anno
- 2010-01-01T00:00:00+01:00 (literal)
- Alternative label
Ledda M, De Carlo F, DEmilia E, Giuliani L, Grimaldi S, and Lisi A. (2010)
Extremely-low frequency magnetic field modulates differentiation and maturation of human and rat primary and multipotent stem cells.
in , 2010
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Ledda M, De Carlo F, DEmilia E, Giuliani L, Grimaldi S, and Lisi A. (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#volumeInCollana
- Note
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Institute of Translational Pharmacology, National Research Council, Rome, Italy; Institute of Translational Pharmacology
. (literal)
- Titolo
- Extremely-low frequency magnetic field modulates differentiation and maturation of human and rat primary and multipotent stem cells. (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#inCollana
- European Journal of Oncology - Library vol. 5, pag.135-147 (literal)
- Abstract
- In the last 15 years, we reported numerous biological effects of extremely-low
frequency electromagnetic fields (ELF-EMF) on different cells types. We
showed morphological and cytoskeletal changes in keratinocyte cell lines
exposed to a 50-Hz 2 mT ELF-EMF. Furthermore, we reported that very high
magnetic field (MF) intensity promotes maturation and differentiation in
newborn cerebellar granule cells, and a 50-Hz 2 mT ELF-EMF produced a
sudden increase in the intracellular calcium level in rat anterior pituitaryderived
AtT20 D16V cells followed by a reorganization of the cytoskeletal
network via polymerization of actin and differentiation of protein expression.
Recently, we showed that a combination of static and alternate EMFs, tuned to
Ca2+ ion cyclotron energy resonance (Ca2+-ICR) was able to trigger human
cardiac stem sell-specific differentiation. In the present review, we report a
summary of the most relevant results that we have reached in the last 7 years, in
particular, we focus the attention on the differentiation effect of ELF-EMF on 3
different types of primary cell culture: human oral keratinocytes (HOK),
newborn rat cerebellar granule neurons (CGN), and human adult cardiac stem
cells (CSC). (literal)
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