Radiotherapy of large target volumes in Hodgkin's lymphoma: normal tissue sparing capability of forward IMRT versus conventional techniques (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Radiotherapy of large target volumes in Hodgkin's lymphoma: normal tissue sparing capability of forward IMRT versus conventional techniques (Articolo in rivista) (literal)

Anno

• 2010-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1186/1748-717X-5-33 (literal)

Alternative label

• Cella, L; Liuzzi, R; Magliulo, M; Conson, M; Camera, L; Salvatore, M; Pacelli, R (2010)
  Radiotherapy of large target volumes in Hodgkin's lymphoma: normal tissue sparing capability of forward IMRT versus conventional techniques
  in Radiation oncology (Online)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Cella, L; Liuzzi, R; Magliulo, M; Conson, M; Camera, L; Salvatore, M; Pacelli, R (literal)

Pagina inizio

• 1 (literal)

Pagina fine

• 10 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.ro-journal.com/content/5/1/33 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 5 (literal)

Rivista

• Radiation oncology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 33 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Institute of Biostructures and Bioimages, National Council of Research (CNR), Via Pansini 5, 80131, Naples, Italy Department of Diagnostic Imaging and Radiation Oncology, University \"Federico II\" of Naples, Via Pansini 5, 80131, Naples, Italy (literal)

Titolo

• Radiotherapy of large target volumes in Hodgkin's lymphoma: normal tissue sparing capability of forward IMRT versus conventional techniques (literal)

Abstract

• Background: This paper analyses normal tissue sparing capability of radiation treatment techniques in Hodgkin's lymphoma with large treatment volume. Methods: 10 patients with supradiaphragmatic Hodgkin's lymphoma and planning target volume (PTV) larger than 900 cm3 were evaluated. Two plans were simulated for each patient using 6 MV X-rays: a conventional multi-leaf (MLC) parallel-opposed (AP-PA) plan, and the same plan with additional MLC shaped segments (forward planned intensity modulated radiation therapy, FPIMRT). In order to compare plans, dose-volume histograms (DVHs) of PTV, lungs, heart, spinal cord, breast, and thyroid were analyzed. The Inhomogeneity Coefficient (IC), the PTV receiving 95% of the prescription dose (V95), the normal tissue complication probability (NTCP) and dose-volume parameters for the OARs were determined. Results: the PTV coverage was improved (mean V95AP-PA = 95.9 and ICAP-PA = 0.4 vs. V95FPIMRT = 96.8 and ICFPIMRT = 0.31, p <= 0.05) by the FPIMRT technique compared to the conventional one. At the same time, NTCPs of lung, spinal cord and thyroid, and the volume of lung and thyroid receiving >= 30 Gy resulted significantly reduced when using the FPIMRT technique. Conclusions: The FPIMRT technique can represent a very useful and, at the same time, simple method for improving PTV conformity while saving critical organs when large fields are needed as in Hodgkin's lymphoma. (literal)

Prodotto di

• Institute of biostructure and bioimaging (IBB) (Istituto)
• Radioterapia, Controlli di Qualità e Sicurezza, Ottimizzazione di Piani di Trattamento (ME.P03.001.002) (Modulo)

Autore CNR

• LUIGI CAMERA (Persona)
• MARIO MAGLIULO (Persona)
• RAFFAELE LIUZZI (Unità di personale interno)
• LAURA CELLA (Unità di personale interno)
• MARCO SALVATORE (Persona)
• ROBERTO PACELLI (Persona)

Incoming links:

Autore CNR di

• LAURA CELLA (Unità di personale interno)
• RAFFAELE LIUZZI (Unità di personale interno)
• MARCO SALVATORE (Persona)
• MARIO MAGLIULO (Persona)
• ROBERTO PACELLI (Persona)
• LUIGI CAMERA (Persona)

Prodotto

• Institute of biostructure and bioimaging (IBB) (Istituto)
• Radioterapia, Controlli di Qualità e Sicurezza, Ottimizzazione di Piani di Trattamento (ME.P03.001.002) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Radiation oncology (Rivista)