http://www.cnr.it/ontology/cnr/individuo/prodotto/ID14017
Detection of colo-rectal liver metastases: prospective comparison of contrast enhanced US, multidetector CT, PET/CT, and 1.5 Tesla MR with extracellular and reticulo-endothelial cell specific contrast agents (Articolo in rivista)
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- Detection of colo-rectal liver metastases: prospective comparison of contrast enhanced US, multidetector CT, PET/CT, and 1.5 Tesla MR with extracellular and reticulo-endothelial cell specific contrast agents (Articolo in rivista) (literal)
- Anno
- 2010-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1007/s00261-009-9555-2 (literal)
- Alternative label
Mainenti PP; Mancini M; Mainolfi C; Camera L; Maurea S; Manchia A; Tanga M; Persico F; Addeo P; D'Antonio D; Speranza A; Bucci L; Persico G; Pace L; Salvatore M (2010)
Detection of colo-rectal liver metastases: prospective comparison of contrast enhanced US, multidetector CT, PET/CT, and 1.5 Tesla MR with extracellular and reticulo-endothelial cell specific contrast agents
in Abdominal imaging
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Mainenti PP; Mancini M; Mainolfi C; Camera L; Maurea S; Manchia A; Tanga M; Persico F; Addeo P; D'Antonio D; Speranza A; Bucci L; Persico G; Pace L; Salvatore M (literal)
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
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- IBB CNR, Via Pansini 5, 80131 Naples, Italy
Department of Biomorphological and Functional Sciences, Section of Radiology, University of Naples ''Federico II'', Via Pansini 5, 80131 Naples, Italy
Department of General Surgery, Geriatry and Endoscopy, University of Naples ''Federico II'', Via Pansini 5, 80131 Naples, Italy
Department of General, Geriatric and Oncological Surgery and Advanced Techniques, University of Naples ''Federico II'', Via Pansini 5, 80131 Naples, Italy (literal)
- Titolo
- Detection of colo-rectal liver metastases: prospective comparison of contrast enhanced US, multidetector CT, PET/CT, and 1.5 Tesla MR with extracellular and reticulo-endothelial cell specific contrast agents (literal)
- Abstract
- Background: To compare contrast-enhanced US (CEUS),
multidetector-CT (MDCT), 1.5 Tesla MR with
extra-cellular (Gd-enhanced) and intracellular (SPIOenhanced)
contrast agents and PET/CT, in the detection
of hepatic metastases from colorectal cancer.
Materials and methods: A total of 34 patients with colorectal
adenocarcinoma underwent preoperatively CEUS,
MDCT, Gd- and SPIO-enhanced MR imaging
(MRI), and PET/CT. Each set of images was reviewed
independently by two blinded observers. The ROC
method was used to analyze the results, which were
correlated with surgical findings, intraoperative US,
histopathology, and MDCT follow-up.
Results: A total of 57 hepatic lesions were identified: 11
hemangiomas, 29 cysts, 1 focal fatty liver, 16 metastases
(dimensional distribution: 5/16 < 5 mm; 3/16 between
5 mm and <10 mm; 8/16 ? 10 mm). Six of 34 patients
were classified as positive for the presence of at least one
metastasis. Considering all the metastases and those
?10 mm, ROC areas showed no significant differences
between Gd- and SPIO-enhanced MRI, which performed
significantly better than the other modalities (P < 0.05).
Considering the lesions <10 mm, ROC areas showed no
significant differences between all modalities; however
MRI presented a trend to perform better than the other
techniques. Considering the patients, ROC areas showed
no significant differences between all the modalities;
however PET/CT seemed to perform better than the
others.
Conclusions: Gd- and SPIO-enhanced MRI seem to be
the most accurate modality in the identification of liver
metastases from colo-rectal carcinoma. PET/CT shows a
trend to perform better than the other modalities in the
identification of patients with liver metastases. (literal)
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