Fully automated synthesis procedure of 4-[18F]fluorobenzaldehyde by commercial synthesizer: Amino-oxi peptide labelling prosthetic group (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Fully automated synthesis procedure of 4-[18F]fluorobenzaldehyde by commercial synthesizer: Amino-oxi peptide labelling prosthetic group (Articolo in rivista) (literal)

Anno

• 2009-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.apradiso.2009.04.008 (literal)

Alternative label

• Speranza A; Ortosecco G; Castaldi E; Nardelli A; Pace L; Salvatore M (2009)
  Fully automated synthesis procedure of 4-[18F]fluorobenzaldehyde by commercial synthesizer: Amino-oxi peptide labelling prosthetic group
  in Applied radiation and isotopes; Pergamon-Elsevier Science Ltd., Oxford (Regno Unito)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Speranza A; Ortosecco G; Castaldi E; Nardelli A; Pace L; Salvatore M (literal)

Pagina inizio

• 1664 (literal)

Pagina fine

• 1669 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.sciencedirect.com/science/article/pii/S0969804309003601 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 67 (literal)

Rivista

• Applied radiation and isotopes (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 6 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 9 (literal)

Note

• Scopu (literal)
• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1) IBB-CNR, Edificio 10, Via Pansini 5, Napoli, Italy 2) Dipartimento di Scienze Biomorfologiche e Funzionali, Università degli Studi di Napoli Federico II, Edificio 10, Via Pansini 5, Napoli, Italy (literal)

Titolo

• Fully automated synthesis procedure of 4-[18F]fluorobenzaldehyde by commercial synthesizer: Amino-oxi peptide labelling prosthetic group (literal)

Abstract

• Automatic synthesis of 4-[18F]fluorobenzaldehyde has been developed by a commercially available TRACERlab(TM) FXF-N synthesis module to be used as prosthetic group for amino-oxy functionalized peptide labelling in clinical routine application. In addition a handmade purification device (HPD) has been setup to perform automatic cartridge purification as well as to back-up the reactor where one-pot synthesis is not applicable. Cartridges for solid phase extraction such as C18, C8, phenyl has been tested to best perform purification as well as activity recovery. Radiochemical yield (RCY) at end of synthesis (EOS) was in average 67% after about 45 min (90% decay corrected at EOB). The RCY of the entire procedure was 54% with a radiochemical purity above 99%. (literal)

Editore

• Pergamon-Elsevier Science Ltd. (Editore)

Prodotto di

• Institute of biostructure and bioimaging (IBB) (Istituto)
• Imaging Morfo-funzionale Integrato delle Patologie del Distretto Toraco-addominale e Sviluppo di Sistemi Integrati di Gestione e Trasmissione di Dati (ME.P06.003.001) (Modulo)

Autore CNR

• ANTONIO SPERANZA (Unità di personale interno)
• MARCO SALVATORE (Persona)

Insieme di parole chiave

• Keywords of "Fully automated synthesis procedure of 4-[18F]fluorobenzaldehyde by commercial synthesizer: Amino-oxi peptide labelling prosthetic group" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• ANTONIO SPERANZA (Unità di personale interno)
• MARCO SALVATORE (Persona)

Prodotto

• Institute of biostructure and bioimaging (IBB) (Istituto)
• Imaging Morfo-funzionale Integrato delle Patologie del Distretto Toraco-addominale e Sviluppo di Sistemi Integrati di Gestione e Trasmissione di Dati (ME.P06.003.001) (Modulo)

Editore di

• Pergamon-Elsevier Science Ltd. (Editore)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Applied radiation and isotopes (Rivista)

Insieme di parole chiave di

• Keywords of "Fully automated synthesis procedure of 4-[18F]fluorobenzaldehyde by commercial synthesizer: Amino-oxi peptide labelling prosthetic group" (Insieme di parole chiave)