http://www.cnr.it/ontology/cnr/individuo/prodotto/ID13983

Assessment of Chest High-Field Magnetic Resonance Imaging in Children and Young Adults With Noncystic Fibrosis Chronic Lung Disease Comparison to High-Resolution Computed Tomography and Correlation With Pulmonary Function (Articolo in rivista)

Type

Articolo in rivista (Classe)
Prodotto della ricerca (Classe)

Label

Assessment of Chest High-Field Magnetic Resonance Imaging in Children and Young Adults With Noncystic Fibrosis Chronic Lung Disease Comparison to High-Resolution Computed Tomography and Correlation With Pulmonary Function (Articolo in rivista) (literal)

Anno

2009-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

10.1097/RLI.0b013e3181b4c1ba (literal)

Alternative label

Montella, S; Santamaria, F; Salvatore, M; Pignata, C; Maglione, M; Iacotucci, P; Mollica, C (2009)
Assessment of Chest High-Field Magnetic Resonance Imaging in Children and Young Adults With Noncystic Fibrosis Chronic Lung Disease Comparison to High-Resolution Computed Tomography and Correlation With Pulmonary Function
in Investigative radiology; Lippincott Williams & Wilkins, Philadelphia (Stati Uniti d'America)
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Montella, S; Santamaria, F; Salvatore, M; Pignata, C; Maglione, M; Iacotucci, P; Mollica, C (literal)

Pagina inizio

532 (literal)

Pagina fine

538 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

http://journals.lww.com/investigativeradiology/pages/default.aspx (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

44 (literal)

Rivista

Investigative radiology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

7 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

9 (literal)

Note

ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

Montella, S: Departments of Pediatrics, Federico II University, Naples, Italy; Santamaria, F: Departments of Pediatrics, Federico II University, Naples, Italy; Salvatore, M: Departments of Diagnostic Imaging, Federico II University, Naples, Italy; Pignata, C: Departments of Pediatrics, Federico II University, Naples, Italy; Maglione, M: Departments of Pediatrics, Federico II University, Naples, Italy; Iacotucci, P: Departments of Pediatrics, Federico II University, Naples, Italy; Mollica, C: Biostructure and Bioimaging Institute, National Research Council, Naples, Italy; IRCCS-SDN Foundation, Naples, Italy (literal)

Titolo

Assessment of Chest High-Field Magnetic Resonance Imaging in Children and Young Adults With Noncystic Fibrosis Chronic Lung Disease Comparison to High-Resolution Computed Tomography and Correlation With Pulmonary Function (literal)

Abstract

Objectives: Magnetic resonance imaging (MRI) has been proposed as a radiation-free alternative to high resolution computed tomography (HRCT) for the assessment and follow-up of chest disorders. Thus far, no study has compared the efficacy of high-field MRI and HRCT in children and adults with noncystic fibrosis (CF) chronic lung disease. The aims of our study were: (1) to assess whether chest high-field MRI is as effective as chest HRCT in identifying pulmonary abnormalities; and (2) to investigate the relationships between the severity and extent of lung disease, and functional data in patients with non-CF chronic lung disease. Materials and Methods: Forty-one subjects (median age, 13.8 years; range, 5.9-29.3 years; 30 children/11 adults) with primary ciliary dyskinesia (n = 14), primary immunodeficiency (n = 14), or recurrent pneumonia (n = 13) underwent pulmonary function tests, chest HRCT (120 kV, dose-modulated mAs) and high-field 3.0-T MRI (HASTE; transversal orientation; repetition time/echo time/flip angle/acquisition time, infinite/92 milliseconds/150°/approximately 90 seconds). HRCT and MRI images were scored in consensus by 2 raters using a modified version of the Helbich scoring system. The maximal score was 25. Results: HRCT and high-field MRI total scores were 11 (range: 1-20) and 11 (range: 1-17), respectively. There was good agreement between the 2 techniques for all scores (r > 0.8). HRCT and MRI total scores, and extent of bronchiectasis scores were significantly related to pulmonary function tests (r = -0.4, P < 0.05). The MRI mucous plugging score was significantly related to pulmonary function tests (r = -0.4, P < 0.05). Conclusions: Chest high-field 3.0-T MRI appears to be as effective as HRCT in assessing the extent and severity of lung abnormalities in non-CF chronic lung diseases, and might be a reliable radiation-free option to HRCT. (literal)

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