Evidence for an elongated dimeric structure of heparin-binding hemagglutinin from Mycobacterium tuberculosis. (Articolo in rivista)

Type
Label
  • Evidence for an elongated dimeric structure of heparin-binding hemagglutinin from Mycobacterium tuberculosis. (Articolo in rivista) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1128/JB.01988-07 (literal)
Alternative label
  • Esposito, C., Pethoukov, M. V., Svergun, D. I., Ruggiero, A., Pedone, C., Pedone, E. & Berisio, R. (2008)
    Evidence for an elongated dimeric structure of heparin-binding hemagglutinin from Mycobacterium tuberculosis.
    in Journal of bacteriology (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Esposito, C., Pethoukov, M. V., Svergun, D. I., Ruggiero, A., Pedone, C., Pedone, E. & Berisio, R. (literal)
Pagina inizio
  • 4749 (literal)
Pagina fine
  • 4753 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 190 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto
  • Pubblicazione su rivista internazionale (literal)
Note
  • Scopu (literal)
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Istituto di Biostrutture e Bioimmagini, C.N.R., I-80134, Napoli, Italy1; European Molecular Biology Lab, Hamburg, c/o DESY, Notkestrasse 85, 22603 Hamburg, Germany2; and Dipartimento delle Scienze Biologiche, Sezione di Biostrutture, Universita` degli Studi di Napoli Federico II, I-80134, Napoli, Italy3 (literal)
Titolo
  • Evidence for an elongated dimeric structure of heparin-binding hemagglutinin from Mycobacterium tuberculosis. (literal)
Abstract
  • Heparin-binding hemagglutinin (HBHA) is a virulence factor of tuberculosis which is responsible for extrapulmonary dissemination of this disease. A thorough biochemical characterization of HBHA has provided experimental evidence of a coiled-coil nature of HBHA. These data, together with the low-resolution structures of a full-length form and a truncated form of HBHA obtained by small-angle X-ray scattering, have unambiguously indicated that HBHA has a dimeric structure with an elongated shape. (literal)
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