http://www.cnr.it/ontology/cnr/individuo/prodotto/ID13717
PET/CT colonography in patients with colorectal polyps: a feasibility study (Articolo in rivista)
- Type
- Label
- PET/CT colonography in patients with colorectal polyps: a feasibility study (Articolo in rivista) (literal)
- Anno
- 2007-01-01T00:00:00+01:00 (literal)
- Alternative label
Mainenti PP, Salvatore B, D'Antonio D, De Falco T, De Palma GD, D'Armiento FP, Bucci L, Pace L, Salvatore M (2007)
PET/CT colonography in patients with colorectal polyps: a feasibility study
in European journal of nuclear medicine and molecular imaging (Print)
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Mainenti PP, Salvatore B, D'Antonio D, De Falco T, De Palma GD, D'Armiento FP, Bucci L, Pace L, Salvatore M (literal)
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- Google Scholar (literal)
- ISI Web of Science (WOS) (literal)
- PubMed (literal)
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- IBB CNR
Department of Biomorphological and Functional Sciences, Section of Radiology, University of Naples \"Federico II\"
Department of General, Geriatric and Oncological Surgery and Advanced Techniques, University of Naples \"Federico II\",
Department of General Surgery, Geriatry and Endoscopy, University of Naples \"Federico II\",
Department of Biomorphological and Functional Sciences, Section of Pathology, University of Naples \"Federico II\", (literal)
- Titolo
- PET/CT colonography in patients with colorectal polyps: a feasibility study (literal)
- Abstract
- Purpose To examine: (1) the feasibility of PET/CT colonography
(PET/CTc) in patients with colorectal polyps; (2)
the impact of metabolic information on CTc interpretation
and, conversely, the impact of morphological information
on PET characterisation of focal colorectal uptake.
Methods Ten patients with colorectal polyps underwent
PET/CTc, followed within 3 h by therapeutic conventional
colonoscopy (CC). A radiologist and a nuclear medicine
physician analysed the PET/CTc images. The agreement of
morphological and metabolic information in the colon and
rectum was evaluated. The sensitivity and specificity of
PET, CT and PET/CT were calculated for colorectal polyps.
Results Seventeen polypoid lesions were identified at CC:
six<=5 mm, six between 6 and 9 mm, and five>=10 mm (four
hyperplastic polyps, 11 tubular adenomas, one adenocarcinoma
and one submucosal lipoma). A total of 20 scans
(supine and prone) were performed in the ten patients: the
agreement of morphological and metabolic information was
excellent in 17 scans, good in two and moderate in one.
PET/CTc showed a sensitivity of 91% for lesions >=6 mm
and a specificity of 100%. The metabolic information did
not disclose any further polyps missed on CTc. The
morphological information permitted correct classification
of all eight instances of focal radiotracer uptake.
Conclusion PET/CTc is a feasible study. Adding a colonographic
protocol to PET/CT images seems to allow correct
characterisation of all cases of colorectal focal radiotracer
uptake. The metabolic information does not seem to
increase the accuracy of CTc. (literal)
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