An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius (Articolo in rivista)

Type
Label
  • An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius (Articolo in rivista) (literal)
Anno
  • 2003-01-01T00:00:00+01:00 (literal)
Alternative label
  • Bartolucci, Simonetta; De Simone, Giuseppina; Galdiero, Stefania; Improta, Roberto; Menchise, Valeria; Pedone, Carlo; Pedone, Emilia; Saviano, Michele (2003)
    An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius
    in Journal of bacteriology (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Bartolucci, Simonetta; De Simone, Giuseppina; Galdiero, Stefania; Improta, Roberto; Menchise, Valeria; Pedone, Carlo; Pedone, Emilia; Saviano, Michele (literal)
Pagina inizio
  • 4285 (literal)
Pagina fine
  • 4289 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 185 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Titolo
  • An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius (literal)
Abstract
  • We report a crystallog. and computational anal. of two mutant forms of the Alicyclobacillus acidocaldarius thioredoxin (BacTrx) done in order to evaluate the contribution of two specific amino acids to the thermostability of BacTrx. Our results suggest that the thermostability of BacTrx may be modulated by mutations affecting the overall electrostatic energy of the protein. (literal)
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