Hemopoietic and angiogenetic progenitors in healthy athletes: different responses to endurance and maximal exercise. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Hemopoietic and angiogenetic progenitors in healthy athletes: different responses to endurance and maximal exercise. (Articolo in rivista) (literal)

Anno

• 2010-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1152/japplphysiol.01344.2009 (literal)

Alternative label

• Maria R. Bonsignore 1,5; Giuseppe Morici 2,5; Roberta Riccioni 3; Alice Huertas 4; Eleonora Petrucci 3; Mario Veca 2; Gualtiero Mariani 3; Anna Bonanno 5; Laura Chimenti 1; Maria Gioia 1; Paolo Palange 4; and Ugo Testa3 (2010)
  Hemopoietic and angiogenetic progenitors in healthy athletes: different responses to endurance and maximal exercise.
  in Journal of applied physiology (1985)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Maria R. Bonsignore 1,5; Giuseppe Morici 2,5; Roberta Riccioni 3; Alice Huertas 4; Eleonora Petrucci 3; Mario Veca 2; Gualtiero Mariani 3; Anna Bonanno 5; Laura Chimenti 1; Maria Gioia 1; Paolo Palange 4; and Ugo Testa3 (literal)

Pagina inizio

• 60 (literal)

Pagina fine

• 67 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 109 (literal)

Rivista

• Journal of applied physiology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1 (literal)

Note

• ISI Web of Science (WOS) (literal)
• PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1Biomedical Department, Internal and Specialistic Medicine (DIBIMIS), Section of Pneumology, University of Palermo, Palermo; 2Department of Experimental Medicine (DIMES), University of Palermo, Palermo; 3Laboratory of Oncology Hematology, ISS, Rome; 4Department of Clinical Medicine, \"La Sapienza\" University, Rome; 5Institute of Biomedicine and Molecular Immunology, National Research Council (CNR), Palermo, Italy (literal)

Titolo

• Hemopoietic and angiogenetic progenitors in healthy athletes: different responses to endurance and maximal exercise. (literal)

Abstract

• Hemopoietic and angiogenetic progenitors in healthy athletes: different responses to endurance and maximal exercise. J Appl Physiol 109: 60 - 67, 2010. First published May 6, 2010; doi:10.1152/japplphysiol.01344.2009.--The effects of endurance or maximal exercise on mobilization of bone marrow-derived hemopoietic and angiogenetic progenitors in healthy subjects are poorly defined. In 10 healthy amateur runners, we collected venous blood before, at the end of, and the day after a marathon race (n ? 9), and before and at the end of a 1.5-km field test (n ? 8), and measured hemopoietic and angiogenetic progenitors by flow cytometry and culture assays, as well as plasma or serum concentrations of several cytokines/growth factors. After the marathon, CD34? cells were unchanged, whereas clonogenetic assays showed decreased number of colonies for both erythropoietic (BFU-E) and granulocyte-monocyte (CFU-GM) series, returning to baseline the morning post-race. Conversely, CD34? cells, BFU-E, and CFU-GM increased after the field test. Angiogenetic progenitors, assessed as CD34?KDR? and CD133?VE-cadherin? cells or as adherent cells in culture expressing endothelial markers, increased after both endurance and maximal exercise but showed a different pattern between protocols. Interleukin- 6 increased more after the marathon than after the field test, whereas hepatocyte growth factor and stem cell factor increased similarly in both protocols. Plasma levels of angiopoietin (Ang) 1 and 2 increased after both types of exercise, whereas the Ang-1-to-Ang-2 ratio or vascular endothelial growth factor-A were little affected. These data suggest that circulating hemopoietic progenitors may be utilized in peripheral tissues during prolonged endurance exercise. Endothelial progenitor mobilization after exercise in healthy trained subjects appears modulated by the type of exercise. Exercise-induced increase in growth factors suggests a physiological trophic effect of exercise on the bone marrow. (literal)

Prodotto di

• Istituto di biomedicina e di immunologia molecolare \"Alberto Monroy\" (IBIM) (Istituto)
• Immunopatologia e Farmacologia Clinica e Sperimentale nelle malattie respiratorie (ME.P01.014.005) (Modulo)
• Modelli ex vivo/in vitro per lo studio dell'immunopatologia e della farmacologia nelle pneumopatie (ME.P01.014.007) (Modulo)
• Immunopatologia e Farmacologia nelle Pneumopatie: studi dei meccanismi molecolari in vivo e in modelli in vitro (ME.P01.014.006) (Modulo)

Autore CNR

• giuseppe morici (Unità di personale esterno)
• MARIA ROSARIA BONSIGNORE (Unità di personale interno)
• ANNA BONANNO (Persona)
• Laura Chimenti (Persona)

Insieme di parole chiave

• Parole chiave di "Hemopoietic and angiogenetic progenitors in healthy athletes: different responses to endurance and maximal exercise." (Insieme di parole chiave)

Incoming links:

Autore CNR di

• ANNA BONANNO (Persona)
• Laura Chimenti (Persona)
• giuseppe morici (Unità di personale esterno)
• MARIA ROSARIA BONSIGNORE (Unità di personale interno)

Prodotto

• Istituto di biomedicina e di immunologia molecolare \"Alberto Monroy\" (IBIM) (Istituto)
• Immunopatologia e Farmacologia nelle Pneumopatie: studi dei meccanismi molecolari in vivo e in modelli in vitro (ME.P01.014.006) (Modulo)
• Immunopatologia e Farmacologia Clinica e Sperimentale nelle malattie respiratorie (ME.P01.014.005) (Modulo)
• Modelli ex vivo/in vitro per lo studio dell'immunopatologia e della farmacologia nelle pneumopatie (ME.P01.014.007) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of applied physiology (Rivista)

Insieme di parole chiave di

• Parole chiave di "Hemopoietic and angiogenetic progenitors in healthy athletes: different responses to endurance and maximal exercise." (Insieme di parole chiave)