Expression of IAPs and alternative splice variants in hepatocellular carcinoma tissues and cells. (Articolo in rivista)

Type
Label
  • Expression of IAPs and alternative splice variants in hepatocellular carcinoma tissues and cells. (Articolo in rivista) (literal)
Anno
  • 2004-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1196/annals.1322.033 (literal)
Alternative label
  • Notarbartolo M, Cervello M, Giannitrapani L, Mali M, Poma P, Dusonchet L, Montalto G,D'Alessandro N. (2004)
    Expression of IAPs and alternative splice variants in hepatocellular carcinoma tissues and cells.
    in Annals of the New York Academy of Sciences
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Notarbartolo M, Cervello M, Giannitrapani L, Mali M, Poma P, Dusonchet L, Montalto G,D'Alessandro N. (literal)
Pagina inizio
  • 289 (literal)
Pagina fine
  • 293 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 1028 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Dipartimento di Scienze Farmacologiche and cDipartimento di Medicina Clinica e delle Patologie Emergenti, Universit√† di Palermo, 90127 Palermo, Italy Istituto di Biomedicina ed Immunologia Molecolare \"Alberto Monroy,\" Consiglio Nazionale delle Ricerche, Via U. La Malfa 153, 90146, Palermo, Italy (literal)
Titolo
  • Expression of IAPs and alternative splice variants in hepatocellular carcinoma tissues and cells. (literal)
Abstract
  • IAPs (inhibitors of apoptosis proteins) might have a major role in the apoptotic resistance that marks many cancers. The studies on IAPs in human HCC have focused on survivin or XIAP, indicating that their new or increased expression in this tumor is associated with a more unfavorable prognosis. The present results corroborate these findings, emphasizing the role that the coordinated expression of different IAPs and alternative splice variants might play in the adverse biology of hepatocellular carcinoma. (literal)
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