UVB radiation prevents skeleton growth and stimulates the expression of stress markers in sea urchin embryos (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• UVB radiation prevents skeleton growth and stimulates the expression of stress markers in sea urchin embryos (Articolo in rivista) (literal)

Anno

• 2005-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.bbrc.2004.12.161 (literal)

Alternative label

• Bonaventura R; Poma V; Costa C; Matranga V (2005)
  UVB radiation prevents skeleton growth and stimulates the expression of stress markers in sea urchin embryos
  in Biochemical and biophysical research communications (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Bonaventura R; Poma V; Costa C; Matranga V (literal)

Pagina inizio

• 150 (literal)

Pagina fine

• 157 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 328 (literal)

Rivista

• Biochemical and biophysical research communications (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 8 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Consiglio Nazionale delle Ricerche, Istituto di Biomedicina e Immunologia Molecolare \"Alberto Monroy\", Sezione Biologia dello Sviluppo, Palermo, Italy (literal)

Titolo

• UVB radiation prevents skeleton growth and stimulates the expression of stress markers in sea urchin embryos (literal)

Abstract

• Ozone depletion results in an increased flux of biologically damaging radiations reaching the earth. Although ultraviolet (UV) penetration is attenuated by the seawater, harmful effects can be still observed at low depths where sea urchin embryos are living. We have used Paracentrotits lividus embryos to study the impacts of UV radiation on their development. Blastula cultures were exposed to different doses of UVB (312 nm) radiations and the resulting endpoint effects were evaluated in terms of embryonic morphological abnormalities, variations in specific gene expression, and changes in the levels of stress proteins. We found that embryos were moderately sensitive to 50 J/m(2) UVB radiation; an increase in the number of developmentally delayed and malformed embryos was detected when increasing doses, up to 1000 J/m(2), were used. Major developmental defects, observed 24 and 48 h after exposure, consisted in the failure of skeleton elongation and patterning. Accordingly, we found a reduction in the number of primary mesenchyme cells that expressed Pl-SM30, a gene coding for one of the specific matrix proteins of the skeleton. The morphological effects observed 1, 24, and 48 h after exposure were correlated with a dose-dependent increase in the level and in the activation of two recognized stress markers, namely hsp70 and p38 MAPk, respectively, consistent with their role in mediating cellular response to stress and suggesting a function in embryo survival. (literal)

Prodotto di

• Istituto di biomedicina e di immunologia molecolare \"Alberto Monroy\" (IBIM) (Istituto)
• Stress Cellulare ed Ambiente (SV.P17.005.001) (Modulo)

Autore CNR

• VERONICA POMA (Unità di personale esterno)
• VALERIA MATRANGA (Unità di personale interno)
• ROSA BONAVENTURA (Unità di personale interno)
• CATERINA COSTA (Unità di personale interno)

Insieme di parole chiave

• Keywords of "UVB radiation prevents skeleton growth and stimulates the expression of stress markers in sea urchin embryos" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• VALERIA MATRANGA (Unità di personale interno)
• CATERINA COSTA (Unità di personale interno)
• ROSA BONAVENTURA (Unità di personale interno)
• VERONICA POMA (Unità di personale esterno)

Prodotto

• Istituto di biomedicina e di immunologia molecolare \"Alberto Monroy\" (IBIM) (Istituto)
• Stress Cellulare ed Ambiente (SV.P17.005.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Biochemical and biophysical research communications (Rivista)

Insieme di parole chiave di

• Keywords of "UVB radiation prevents skeleton growth and stimulates the expression of stress markers in sea urchin embryos" (Insieme di parole chiave)