From Wood to Bone: new processes to develop hierarchically organized bone scaffold (Comunicazione a convegno)

Type
Label
  • From Wood to Bone: new processes to develop hierarchically organized bone scaffold (Comunicazione a convegno) (literal)
Anno
  • 2009-01-01T00:00:00+01:00 (literal)
Alternative label
  • Sprio S.; Ruffini A.; Tampieri A. (2009)
    From Wood to Bone: new processes to develop hierarchically organized bone scaffold
    in European Congress and Exhibition on Advanced Materials and Processes, Glasgow
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Sprio S.; Ruffini A.; Tampieri A. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • In: EUROMAT 2009 - European Congress and Exhibition on Advanced Materials and Processes (Glasgow, 07-10 Settembre 2009). (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto
  • In the last decade there is an increasing demand for materials that can potentially replace, repair or even regenerate injured or diseased tissues. Parallely in the orthopaedic field it has been recorded an increasing need to replace traditional autograft and allograft and to perform repair strategies with mechanically and biologically functional constructs that support the wound site and hasten the body's natural repair mechanism until bone has filled the defect. Natural human bone is a porous biohybrid composite with an interesting structure exhibiting as well gradients of density and anisotropic properties: in fact bone, as the majority of the biostructures, is characterized by a complex hierarchy of structures and presents anisotropic structural features able to provide stability against bending and buckling. For this purpose, the chemistry and morphology of the synthetic scaffold should approach the ones of natural bone. Chemically, hydroxyapatite (HA) is considered as the election material for bone substitutions, due to its close similarity with the mineral phase of bone tissue. The morphology of the human bone is very complex, characterized by a complex hierarchic structure exhibiting both gradients of density and anisotropic properties, which confer its unique properties of lightness, resistance, elasticity and capacity to self-regenerate following trauma of limited severity. The peculiar structure of bone also allows an efficient distribution of the mechanical loads up to the smallest trabeculae, where the strain-sensing mechanism exhibited by the osteocyte cells can take place and activate the permanent bone remodelling process. This mechanism allows the continuous re-arrangement of the bone tissue in presence of biophysical stimuli from the environment, so that the local damage is minimized and the functionality of the bone as a whole is optimized. An optimal biophysical response can be expressed only by a scaffold endowed with a structure exhibiting a hi (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • CNR-ISTEC, Faenza (literal)
Titolo
  • From Wood to Bone: new processes to develop hierarchically organized bone scaffold (literal)
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