Development of Hydroxyapatite / Calcium Silicate Composites for biomedical applications (Abstract/Poster in convegno)

Type
Label
  • Development of Hydroxyapatite / Calcium Silicate Composites for biomedical applications (Abstract/Poster in convegno) (literal)
Anno
  • 2009-01-01T00:00:00+01:00 (literal)
Alternative label
  • Sprio S.; Celotti G.; Landi E.; Tampieri A. (2009)
    Development of Hydroxyapatite / Calcium Silicate Composites for biomedical applications
    in European Congress and Exhibition on Advanced Materials and Processes, Glasgow (Regno Unito)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Sprio S.; Celotti G.; Landi E.; Tampieri A. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • In: EUROMAT 2009 - European Congress and Exhibition on Advanced Materials and Processes (Glasgow (Regno Unito), 07-10 Settembre 2009). (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto
  • The substitution of long and load-bearing bone segments is one of the most relevant challenges in the field of orthopaedic surgery, and has enormous societal and economic impact. The optimal solution to face this challenge is the development of a bioactive scaffold, able to promote the formation of new bone tissue and enhanced mechanical properties, to sustain the bio-mechanic load during the bone regeneration process. Although hydroxyapatite (HA) is the election material for bone replacement, its low mechanical strength exhibited by HA hampers any application as load-bearing scaffolds. The use of bioinert ceramic phases to reinforce HA scaffolds often results in HA decomposition at high temperatures and the formation of undesired secondary phases which also compromise the final mechanical strength. Calcium silicates induce HA formation in physiological conditions and are characterized by remarkable flexure strength; thus composites HA / calcium silicates were prepared and the related properties evaluated, especially in term of phase composition and mechanical properties. The resulting composites exhibited high density and no secondary phase formation occurred, even after sintering at 1500°C; flexure strength strongly increased compared to HA alone obtained in the same process conditions and elastic modulus remains in the range of the cortical bone. On the basis of these results, hysdroxyapatite/calcium silicate composites represent a promising class of materials for potential load-bearing applications (literal)
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  • CNR-ISTEC, Faenza (literal)
Titolo
  • Development of Hydroxyapatite / Calcium Silicate Composites for biomedical applications (literal)
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