Division protein interaction web: identification of a phylogenetically conserved common interactome between Streptococcus pneumoniae and Escherichia coli. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Division protein interaction web: identification of a phylogenetically conserved common interactome between Streptococcus pneumoniae and Escherichia coli. (Articolo in rivista) (literal)

Anno

• 2008-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1099/mic.0.2008/018697-0 (literal)

Alternative label

• Maggi S; Massidda O; Luzi G; Fadda D; Paolozzi L; Ghelardini P. (2008)
  Division protein interaction web: identification of a phylogenetically conserved common interactome between Streptococcus pneumoniae and Escherichia coli.
  in Microbiology (N.Y.)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Maggi S; Massidda O; Luzi G; Fadda D; Paolozzi L; Ghelardini P. (literal)

Pagina inizio

• 3042 (literal)

Pagina fine

• 3052 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 154 (literal)

Rivista

• Microbiology (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Dipartimento di Biologia, Universita` Tor Vergata, Roma, Italy Dipartimento di Medicina Interna, Universita` La Sapienza, Roma, Italy Dipartimento di Scienze e Tecnologie Biomediche, Sez. Microbiologia Medica, Cagliari, Italy Istituto di Biologia e Patologia Molecolare del CNR, Roma, Italy (literal)

Titolo

• Division protein interaction web: identification of a phylogenetically conserved common interactome between Streptococcus pneumoniae and Escherichia coli. (literal)

Abstract

• The ability of each of the 11 Streptococcus pneumoniae division proteins to interact with itself and with each of the remaining proteins was studied in 66 combinations of protein pairs, using a bacterial two-hybrid system. Interactions (homo- or hetero-dimerizations) were detected between 37 protein pairs, whereas 29 protein pairs did not interact. In some cases, positive interactions of the S. pneumoniae proteins were confirmed by co-immunoprecipitation experiments in Escherichia coli. Comparison between the S. pneumoniae division protein interaction web and that of E. coli, the only micro-organisms for which the whole division interactome has been described systematically, was also performed. At least nine division proteins, ZapA, FtsZ, FtsA, FtsK, FtsQ/DivIB, FtsB/DivIC, FtsL, FtsI and FtsW, are believed to have a conserved function between these bacteria and thus we may say that a significant part of the interactions are ; conserved. Out of 45 protein pairs tested in both bacteria, 30 showed the same behaviour: 23 interacted while seven did not. In agreement with these results, cross-interactions between S. pneumoniae proteins and the corresponding E. coli orthologues were observed. Taken together, these results suggest a phylogenetically conserved minimal common interactome of the division proteins. (literal)

Prodotto di

• Struttura e funzione di Acidi nucleici e Cromatina. Epigenetica (SV.P14.009.001) (Modulo)
• Institute of molecular biology and pathology (IBPM) (Istituto)

Autore CNR

• PATRIZIA GHELARDINI (Unità di personale interno)

Insieme di parole chiave

• Keywords of "Division protein interaction web: identification of a phylogenetically conserved common interactome between Streptococcus pneumoniae and Escherichia coli." (Insieme di parole chiave)

Incoming links:

Autore CNR di

• PATRIZIA GHELARDINI (Unità di personale interno)

Prodotto

• Institute of molecular biology and pathology (IBPM) (Istituto)
• Struttura e funzione di Acidi nucleici e Cromatina. Epigenetica (SV.P14.009.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Microbiology (Rivista)

Insieme di parole chiave di

• Keywords of "Division protein interaction web: identification of a phylogenetically conserved common interactome between Streptococcus pneumoniae and Escherichia coli." (Insieme di parole chiave)