Greatwall kinase: a nuclear protein required for proper chromosome condensation and mitotic progression in Drosophila. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Greatwall kinase: a nuclear protein required for proper chromosome condensation and mitotic progression in Drosophila. (Articolo in rivista) (literal)

Anno

• 2004-01-01T00:00:00+01:00 (literal)

Alternative label

• J. Yu; S.L. Fleming; B. Williams; E.V. Williams; Z. Li; P. Somma; C.L. Rieder; M.L. Goldberg (2004)
  Greatwall kinase: a nuclear protein required for proper chromosome condensation and mitotic progression in Drosophila.
  in The Journal of cell biology
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• J. Yu; S.L. Fleming; B. Williams; E.V. Williams; Z. Li; P. Somma; C.L. Rieder; M.L. Goldberg (literal)

Pagina inizio

• 487 (literal)

Pagina fine

• 492 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 164 (literal)

Rivista

• ?The ?Journal of cell biology (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Cornell University Ithaca USA, CNR (literal)

Titolo

• Greatwall kinase: a nuclear protein required for proper chromosome condensation and mitotic progression in Drosophila. (literal)

Abstract

• Mutations in the Drosophila gene greatwall cause improper chromosome condensation and delay cell cycle progression in larval neuroblasts. Chromosomes are highly undercondensed, particularly in the euchromatin, but nevertheless contain phosphorylated histone H3, condensin, and topoisomerase II. Cells take much longer to transit the period of chromosome condensation from late G(2) through nuclear envelope breakdown. Mutant cells are also subsequently delayed at metaphase, due to spindle checkpoint activity. These mutant phenotypes are not caused by spindle aberrations, by global defects in chromosome replication, or by activation of a caffeine-sensitive checkpoint. The Greatwall proteins in insects and vertebrates are located in the nucleus and belong to the AGC family of serine/threonine protein kinases; the kinase domain of Greatwall is interrupted by a long stretch of unrelated amino acids. (literal)

Prodotto di

• Institute of molecular biology and pathology (IBPM) (Istituto)

Autore CNR

• MARIA PATRIZIA SOMMA (Unità di personale interno)

Incoming links:

Prodotto

• Institute of molecular biology and pathology (IBPM) (Istituto)

Autore CNR di

• MARIA PATRIZIA SOMMA (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• ?The ?Journal of cell biology (Rivista)