Che-1/AATF, a multivalent adaptor connecting transcriptional regulation,checkpoint control, and apoptosis. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Che-1/AATF, a multivalent adaptor connecting transcriptional regulation,checkpoint control, and apoptosis. (Articolo in rivista) (literal)

Anno

• 2007-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1139/O07-062 (literal)

Alternative label

• Passananti C;Floridi A; Fanciulli M. (2007)
  Che-1/AATF, a multivalent adaptor connecting transcriptional regulation,checkpoint control, and apoptosis.
  in Biochemistry and cell biology (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Passananti C;Floridi A; Fanciulli M. (literal)

Pagina inizio

• 447 (literal)

Pagina fine

• 483 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni

• 28th International West Coast Chromatin Chromosomes Conference (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 85 (literal)

Rivista

• Biochemistry and cell biology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 4 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Istituto di Biologia e Patologia Molecolari, CNR,Rome, Italy; Department of Experimental Medicine, University of L'Aquila, L'Aquila, Italy; Laboratory B, Experimental Research Center, Department of Therapeutic Programs Development, Regina Elena Cancer Institute, Rome, Italy. (literal)

Titolo

• Che-1/AATF, a multivalent adaptor connecting transcriptional regulation,checkpoint control, and apoptosis. (literal)

Abstract

• Che-1/AATF (Che-1) was originally characterized as an interacting protein for RNA polymerase II. In addition to transcriptional regulation, the evidence suggests that Che-1 has a viral factor-like S phase promoting role in counteracting Rb repression to facilitate E2F-dependent transactivation during G(I)-S transition. Recently, Che-1 was found to play an important role in the DNA damage response and cell-cycle checkpoint control. Genetic studies in mice revealed that Che-1 is essential for preimplantation development and the establishment of embryonic gene expression. Importantly, several findings showed that Che-1 participates in inhibiting apoptotic process. Thus, Che-1 emerges as an important adaptor that connects transcriptional regulation, cell-cycle progression, checkpoint control, and apoptosis. (literal)

Prodotto di

• Institute of molecular biology and pathology (IBPM) (Istituto)
• Controllo di proliferazione, differenziamento e morte cellulare (SV.P15.010.001) (Modulo)

Autore CNR

• CLAUDIO PASSANANTI (Persona)

Incoming links:

Prodotto

• Institute of molecular biology and pathology (IBPM) (Istituto)
• Controllo di proliferazione, differenziamento e morte cellulare (SV.P15.010.001) (Modulo)

Autore CNR di

• CLAUDIO PASSANANTI (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Biochemistry and cell biology (Rivista)