http://www.cnr.it/ontology/cnr/individuo/prodotto/ID11448
Duplication, divergence and formation of novel protein topologies. (Articolo in rivista)
- Type
- Label
- Duplication, divergence and formation of novel protein topologies. (Articolo in rivista) (literal)
- Anno
- 2006-01-01T00:00:00+01:00 (literal)
- Alternative label
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Vogel C; Morea V (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Note
- PubMe (literal)
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Institute for Cellular and Molecular Biology, University of Texas at Austin, TX;
CNR, Institute of Molecular Biology and Pathology, c/o Department of Biochemical Sciences, University La Sapienza, Rome, Italy. (literal)
- Titolo
- Duplication, divergence and formation of novel protein topologies. (literal)
- Abstract
- The rearrangement or permutation of protein substructures
is an important mode of divergence. Recent work(1)
explored one possible underlying mechanism called
permutation-by-duplication, which produces special
forms of motif rearrangements called circular permutations.
Permutation-by-duplication, involving gene
duplication, fusion and truncation, can produce fully
functional intermediate proteins(1) and thus represents a
feasible mechanism of protein evolution. In spite of this,
circular permutations are relatively rare and we discuss
possible reasons for their existence. (literal)
- Prodotto di
- Autore CNR
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