http://www.cnr.it/ontology/cnr/individuo/prodotto/ID11447
Non coding RNA and brain (Articolo in rivista)
- Type
- Label
- Non coding RNA and brain (Articolo in rivista) (literal)
- Anno
- 2006-01-01T00:00:00+01:00 (literal)
- Alternative label
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Presutti C., Rosati J ., Vincenti S. and Nasi S . (literal)
- Pagina inizio
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Presutti C, Vincenti S: Dip. Genetica e Biologia Molecolare, Università Sapienza
Rosati J, Nasi S: IBPM CNR (literal)
- Titolo
- Non coding RNA and brain (literal)
- Abstract
- Small non coding RNAs are a group of very different RNA molecules, present in virtually all cells,
with a wide spectrum of regulatory functions which include RNA modification and regulation of
protein synthesis. They have been isolated and characterized in all organisms and tissues, from
Archaeobacteria to mammals. In mammalian brain there are a number of these small molecules,
which are involved in neuronal differentiation as well as, possibly, in learning and memory. In this
manuscript, we analyze the present knowledge about the function of the most important groups of
small non-coding RNA present in brain: small nucleolar RNAs, small cytoplasmic RNAs, and
microRNAs. The last ones, in particular, appear to be critical for dictating neuronal cell identity
during development and to play an important role in neurite growth, synaptic development and
neuronal plasticity. (literal)
- Prodotto di
- Autore CNR
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