Effect of substrate mechanical properties on cell activities (Abstract/Poster in atti di convegno)

Type

• Prodotto della ricerca (Classe)
• Abstract/Poster in atti di convegno (Classe)

Label

• Effect of substrate mechanical properties on cell activities (Abstract/Poster in atti di convegno) (literal)

Anno

• 2006-01-01T00:00:00+01:00 (literal)

Alternative label

• A.Borzacchiello,D.Guarnieri,M.De Micco,S.Zeppetelli,P.A.Netti,C.Pedone,D.Marasco,A.Saporito,M.Ruvo. (2006)
  Effect of substrate mechanical properties on cell activities
  in Internatinal conference on advances in biomaterials for drug delivery and regenerative medicine, Capri
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• A.Borzacchiello,D.Guarnieri,M.De Micco,S.Zeppetelli,P.A.Netti,C.Pedone,D.Marasco,A.Saporito,M.Ruvo. (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto

• The introduction of biomolecules to polymer surfaces has become a relevant tool for controlling cell-biomaterial interaction. The aim of this work was to investigate on the role of mechanical properties of matrix in biological recognition. To do this, we modulated mechanical properties of hydrogels made of polyethylene glycol diacrylate (PEGDA), known for its antiadhesive properties, by varying polymer percentage. In addition, PEGDA molecules were bioactivated with RGD-peptides, well known for its ability to promote cellular attachment by binding to integrin receptors. Furthermore, by keeping constant RGD concentration and by varying PEGDA percentage, we observed only the effect of substrate stiffness, and not of biochemical signals, on cell behaviour. Mechanical properties of hydrogels were characterized by DMA and compression tests. Cell response to bioactive matrices was evaluated in relation to biological parameters, such as cell morphology, viability, adhesion and migration. (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• P.A.Netti, D.Guarnier,M.De Micco :DIMP(Università degli Studi di Napoli Federico II) C.Pedone,D.Marasco,A.Saporito,M.Ruvo:Istituto Biostrutture e Bioimmagini CNR (literal)

Titolo

• Effect of substrate mechanical properties on cell activities (literal)

Prodotto di

• Istituto per i materiali compositi e biomedici (IMCB) (Istituto)
• Biomateriali ed ingegneria dei tessuti (PM.P02.004.002) (Modulo)

Autore CNR

• STEFANIA ZEPPETELLI (Unità di personale esterno)
• ASSUNTA BORZACCHIELLO (Unità di personale interno)

Incoming links:

Autore CNR di

• ASSUNTA BORZACCHIELLO (Unità di personale interno)
• STEFANIA ZEPPETELLI (Unità di personale esterno)

Prodotto

• Istituto per i materiali compositi e biomedici (IMCB) (Istituto)
• Biomateriali ed ingegneria dei tessuti (PM.P02.004.002) (Modulo)