http://www.cnr.it/ontology/cnr/individuo/prodotto/ID113543

Composite technology to design tissue engineering scaffolds (Abstract/Poster in atti di convegno)

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Composite technology to design tissue engineering scaffolds (Abstract/Poster in atti di convegno) (literal)

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L.Ambrosio, S.Battista, A. Borzacchiello, C.Borselli, F Causa, P. Netti, S. Zeppetelli (2004)
Composite technology to design tissue engineering scaffolds
in Ceramic, Cells and Tissues: Materilas for Tissue Engineering, Faenza
(literal)

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L.Ambrosio, S.Battista, A. Borzacchiello, C.Borselli, F Causa, P. Netti, S. Zeppetelli (literal)

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The implementation of the composite technology demonstrated the feasibility to prepare scaffolds for the reconstruction of tendon and ligament where optimal cell interaction and mechanical properties are needed. By using the appropriate rate of Poly(Õ{caprolactone) and Hydroxyapatite is possible to obtain scaffolds with mechanical properties in the range to that of spongy bone, and optimal human osteoblast interaction. The results obtained on Collagen gel and Collagen/Hyaluronic Acid composite gel in presence of different cell lines, indicate the possibility to control cell proliferation by modulating the physical/chemical properties of the material. On collagen gels cells were observed to adhere and proliferate and as results an optimum value of the gel¡¦s stiffness/concentration that promote cell activity, was identified. The collagen/hyaluronic acid composite showed appropriate rheological properties to be used as gel for cell carrier. (literal)

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