The Drosophila HOAP protein is required for telomere capping. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• The Drosophila HOAP protein is required for telomere capping. (Articolo in rivista) (literal)

Anno

• 2003-01-01T00:00:00+01:00 (literal)

Alternative label

• Cenci G, Siriaco G, Raffa GD, Kellum R, Gatti M. (2003)
  The Drosophila HOAP protein is required for telomere capping.
  in Nature cell biology
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Cenci G, Siriaco G, Raffa GD, Kellum R, Gatti M. (literal)

Pagina inizio

• 82 (literal)

Pagina fine

• 84 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 5 (literal)

Rivista

• Nature cell biology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• M. Gatti a disposizione dell'IBPM (literal)

Note

• ISI Web of Science (WOS) (literal)

Titolo

• The Drosophila HOAP protein is required for telomere capping. (literal)

Abstract

• HOAP (HP1/ORC-associated protein) has recently been isolated from Drosophila melanogaster embryos as part of a cytoplasmic complex that contains heterochromatin protein 1 (HP1) and the origin recognition complex subunit 2 (ORC2). Here, we show that caravaggio, a mutation in the HOAP-encoding gene, causes extensive telomere-telomere fusions in larval brain cells, indicating that HOAP is required for telomere capping. Our analyses indicate that HOAP is specifically enriched at mitotic chromosome telomeres, and strongly suggest that HP1 and HOAP form a telomere-capping complex that does not contain ORC2. (literal)

Prodotto di

• Institute of molecular biology and pathology (IBPM) (Istituto)

Autore CNR

• MAURIZIO GATTI (Persona)

Incoming links:

Autore CNR di

• MAURIZIO GATTI (Persona)

Prodotto

• Institute of molecular biology and pathology (IBPM) (Istituto)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Nature cell biology (Rivista)