http://www.cnr.it/ontology/cnr/individuo/prodotto/ID11047

Stearoyl-coenzyme A desaturase gene polymorphism and milk fatty acid composition in Italian Holsteins (Articolo in rivista)

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Stearoyl-coenzyme A desaturase gene polymorphism and milk fatty acid composition in Italian Holsteins (Articolo in rivista) (literal)

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Alternative label

Marcello Mele; Giuseppe Conte; Bianca Castiglioni; Stefania Chessa; Nicolò Pietro Paolo Macciotta; Andrea Serra; Arianna Buccioni; Giulio Pagnacco; Pierlorenzo Secchiari (2007)
Stearoyl-coenzyme A desaturase gene polymorphism and milk fatty acid composition in Italian Holsteins
in Journal of dairy science; American Dairy Science Association-ADSA, Champaign (Stati Uniti d'America)
(literal)

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Marcello Mele; Giuseppe Conte; Bianca Castiglioni; Stefania Chessa; Nicolò Pietro Paolo Macciotta; Andrea Serra; Arianna Buccioni; Giulio Pagnacco; Pierlorenzo Secchiari (literal)

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Pubblicazione scientifica riguardante lo studio di un polimorfismo del gene SCD (stearoyl-CoA desaturasi) che influenza le produzioni di latte in bovine di razza Frisona. (literal)

Note

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Marcello Mele, Giuseppe Conte, Andrea Serra, Pierlorenzo Secchiari - Dipartimento di Agronomia e Gestione dell'Agroecosistema, University of Pisa, Italy; Bianca Castiglioni - Istituto di Biologia e Biotecnologia Agraria, CNR, Milan, Italy; Stefania Chessa, Giulio Pagnacco - Dipartimento di Scienze e Tecnologie Vetehnarie per Ia Sicurezza Alimentare, University of Milan, Italy; Nicolò Pietro Paolo Macciotta - Dipartimento di Scienze Zootecniche, University of Sassari, Sassari, Italy; Arianna Buccioni - Dipartimento di Scienze Zootecniche, University of Florence, Florence, Italy (literal)

Titolo

Stearoyl-coenzyme A desaturase gene polymorphism and milk fatty acid composition in Italian Holsteins (literal)

Abstract

Milk fatty acid composition is a parameter of great interest for evaluation of nutritional quality of milk. Stearoyl-CoA desaturase (SCD) is a key enzyme in mammary lipid metabolism because it is able to add a double bond in the cis Ä9-position in a large spectrum of medium- and long-chain fatty acids. A polymorphism with 2 alleles (A and V) in the fifth exon of the SCD gene has been reported. The effect of SCD genotype on individual milk fatty acid composition and on cis-9 unsaturated/saturated fatty acid ratios of 297 Holstein Italian Friesian cows was investigated in this paper. The SCD genotypes were determined by using a single strand conformation polymorphism method. Relative frequencies of SCD genotypes were 27, 60, and 13% for AA, AV, and VV, respectively. Milk of AA cows had a greater content of cis-9 C18:1 and total monounsaturated fatty acids and a higher C14:1/C14 ratio than did milk of VV cows. The relative contribution of SCD genotype to variation of monounsaturated fatty acids, cis-9 C18:1, and cis-9 C14:1 was 5, 4, and 7.7%, respectively. No significant differences were detected between SCD genotypes in the milk content of cis-9, trans-11 C18:2. Results of the present work provide some indication of an association between SCD locus and the fatty acid profile in the examined sample of Italian Holsteins, thus suggesting a possible role of this gene in the genetic variation of milk nutritional properties. (literal)

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