Semi-automatic misalignment correction for a small animal micro-CT scanner with variable geometry (Abstract/Poster in convegno)

Type
Label
  • Semi-automatic misalignment correction for a small animal micro-CT scanner with variable geometry (Abstract/Poster in convegno) (literal)
Anno
  • 2010-01-01T00:00:00+01:00 (literal)
Alternative label
  • Panetta D.; Belcari N.; Del Guerra A.; Salvadori P. A. (2010)
    Semi-automatic misalignment correction for a small animal micro-CT scanner with variable geometry
    in The first international conference on image formation in X-ray computed tomography, Salt Lake City, UT, USA, June 6-9, 2010
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Panetta D.; Belcari N.; Del Guerra A.; Salvadori P. A. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • In: The first international conference on image formation in X-ray computed tomography (Salt Lake City, UT, USA, June 6-9 2010). (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto
  • An enginereed micro-CT scanner for in vivo imaging of small animals (Xalt, which stands for X-ray AnimaL Tomograph) has been recently built at the Institute of Clinical Physiology of the National Research Council (IFC-CNR, Pisa, Italy), in partnership with the University of Pisa. The Xalt scanner is a cone beam micro-CT based on a 2-dimensional flat-panel detector and microfocus x-ray source. The magnification and detector orientation can be manually varied to select the spatial resolution, field of view (FoV) and sensitivity that match the needs of several different imaging protocols for mice, rats and test tubes. Even with high precision mechanical assembly, recalibration for geometric misalignments is necessary after each modification of the scanner geometry. To avoid the burden of geometric recalibration, a semi-automatic cone beam calibration method has been applied and integrated in the reconstruction software. The calibration method does not require measurements on specific phantoms, as it is based on the recovery of redundancies in the projection data of generic objects that are lost when the scanner components are out of alignment. By using this method, our variable geometry micro-CT can be realigned at each scan by analyzing the projection data set (or part of it), without additional phantom measurements. To assess the reliability of our method we have made several acquisitions on a phantom, each carried after mechanical stress of the positioning system. We showed that the semi-automatic calibration method is an effective aid for a fast and reliable scanner realignment, without additional acquisitions. Index Terms-MicroCT, geometrical calibration, variable geometry scanners (literal)
Note
  • Poster (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • CNR-IFC, Pisa, Dipartimento di Fisica, Università di Pisa (literal)
Titolo
  • Semi-automatic misalignment correction for a small animal micro-CT scanner with variable geometry (literal)
Abstract
  • An enginereed micro-CT scanner for in vivo imaging of small animals (Xalt, which stands for X-ray AnimaL Tomograph) has been recently built at the Institute of Clinical Physiology of the National Research Council (IFC-CNR, Pisa, Italy), in partnership with the University of Pisa. The Xalt scanner is a cone beam micro-CT based on a 2-dimensional flat-panel detector and microfocus x-ray source. The magnification and detector orientation can be manually varied to select the spatial resolution, field of view (FoV) and sensitivity that match the needs of several different imaging protocols for mice, rats and test tubes. Even with high precision mechanical assembly, recalibration for geometric misalignments is necessary after each modification of the scanner geometry. To avoid the burden of geometric recalibration, a semi-automatic cone beam calibration method has been applied and integrated in the reconstruction software. The calibration method does not require measurements on specific phantoms, as it is based on the recovery of redundancies in the projection data of generic objects that are lost when the scanner components are out of alignment. By using this method, our variable geometry micro-CT can be realigned at each scan by analyzing the projection data set (or part of it), without additional phantom measurements. To assess the reliability of our method we have made several acquisitions on a phantom, each carried after mechanical stress of the positioning system. We showed that the semi-automatic calibration method is an effective aid for a fast and reliable scanner realignment, without additional acquisitions. (literal)
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