http://www.cnr.it/ontology/cnr/individuo/prodotto/ID109073
Cumulative radiation dose from medical testing in grown-up patients with congenital heart disease (Abstract in rivista)
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- Cumulative radiation dose from medical testing in grown-up patients with congenital heart disease (Abstract in rivista) (literal)
- Anno
- 2007-01-01T00:00:00+01:00 (literal)
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Ait-Ali L.; Botto S.; Andreassi M. G.; Festa P.; Picano E. (literal)
- Convegno
- European Heart Journal (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
- In: European Heart Journal, vol. 28 Oxford Journals, 2007. (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto
- Background: The \"Biological effects of Ionizing Radiation\" (BEIR VII,2005) underlines \"the need of studies of infant who are exposed to diagnostic radiation\". Aim: to assess the individual cumulative lifetime radiological dose in grown up congenital heart disease (GUCH) patients. Methods: In 41 consecutive operated GUCH patient (24 males, age= 27±9 years old), followed in our outpatient clinic, a cumulative radiological history was collected with a structured questionnaire and access to a lifetime hospital records. All patient underwent at least one surgical intervention during the infancy for Tetralogy of Fallot (n=18), Aortic coarctation (n=10), anatomical/functional univentricular heart (n=8), other congenital heart disease (n=5) The cumulative exposure was expressed in milliSievert and derived from average effective dose values of individual examinations proposed by the European Commission Medical Imaging Guidelines (2001) and most recent peer reviewed literature. The associated cancer risk was estimated from BEIR VII, 2005 document. Results: On average, cumulative exposure was 22.3±12.4 (mean±SD) mSv per patient equivalent to about 1115±620 chest x-rays. Diagnostic and interventional catheterization accounted for the most important sources of exposure (65% of total collective effective dose, see figure). The median cumulative dose gave an average extra-risk of cancer of about 1 out of 200 patients (range, 1 in 448 to 1 out of 58). Conclusion: the average contemporary GUCH patient is exposed to a significant cumulative radiological effective dose, from diagnostic and therapeutic interventions. Every effort should be done to justify the indications and to optimise dose delivery during ionizing testing, especially in children, in order to minimize the associated cancer risk. (literal)
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- Cumulative radiation dose from medical testing in grown-up patients with congenital heart disease (literal)
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