Validation of an elastic registration technique to estimate anatomical lung modification in Non-Small-Cell Lung Cancer Tomotherapy. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Validation of an elastic registration technique to estimate anatomical lung modification in Non-Small-Cell Lung Cancer Tomotherapy. (Articolo in rivista) (literal)

Anno

• 2011-01-01T00:00:00+01:00 (literal)

Alternative label

• Faggiano E. 1,2, Cattaneo G.M. 3, Ciavarro C. 4, Dell'oca I. 5, Persano D. 6, Calandrino R. 3, Rizzo G. 7 (2011)
  Validation of an elastic registration technique to estimate anatomical lung modification in Non-Small-Cell Lung Cancer Tomotherapy.
  
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Faggiano E. 1,2, Cattaneo G.M. 3, Ciavarro C. 4, Dell'oca I. 5, Persano D. 6, Calandrino R. 3, Rizzo G. 7 (literal)

Pagina inizio

• 31 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 6 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• Corresponding author: G. Rizzo (giovanna.rizzo@ibfm.cnr.it) IF 2010: 2.409 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1. IBFM-CNR, Segrate (MI). 2. Dipartimento di Bioingegneria, Politecnico di Milano, Milano. 3. Servizio di Fisica Sanitaria, Istituto Scientifico San Raffaele, Milano. 4. IRCCS Istituto Ortopedico Galeazzi, Milano. 5. U.O. Radioterapia, Istituto Scientifico San Raffaele, Milano. 6. Sciences Institute, National University of General Sarmiento, Buenos Aires (Argentina). 7. U.O. Medicina Nucleare, Istituto Scientifico San Raffaele Milano. (literal)

Titolo

• Validation of an elastic registration technique to estimate anatomical lung modification in Non-Small-Cell Lung Cancer Tomotherapy. (literal)

Abstract

• BACKGROUND: The study of lung parenchyma anatomical modification is useful to estimate dose discrepancies during the radiation treatment of Non-Small-Cell Lung Cancer (NSCLC) patients. We propose and validate a method, based on free-form deformation and mutual information, to elastically register planning kVCT with daily MVCT images, to estimate lung parenchyma modification during Tomotherapy. METHODS: We analyzed 15 registrations between the planning kVCT and 3 MVCT images for each of the 5 NSCLC patients. Image registration accuracy was evaluated by visual inspection and, quantitatively, by Correlation Coefficients (CC) and Target Registration Errors (TRE). Finally, a lung volume correspondence analysis was performed to specifically evaluate registration accuracy in lungs. RESULTS: Results showed that elastic registration was always satisfactory, both qualitatively and quantitatively: TRE after elastic registration (average value of 3.6 mm) remained comparable and often smaller than voxel resolution. Lung volume variations were well estimated by elastic registration (average volume and centroid errors of 1.78% and 0.87 mm, respectively). CONCLUSIONS: Our results demonstrate that this method is able to estimate lung deformations in thorax MVCT, with an accuracy within 3.6 mm comparable or smaller than the voxel dimension of the kVCT and MVCT images. It could be used to estimate lung parenchyma dose variations in thoracic Tomotherapy. (literal)

Prodotto di

• Tecniche di elaborazione dati e immagini (ME.P06.005.002) (Modulo)
• Institute of molecular bioimaging and physiology (IBFM) (Istituto)

Autore CNR

• ELENA FAGGIANO (Unità di personale esterno)
• GIOVANNA RIZZO (Unità di personale interno)

Incoming links:

Autore CNR di

• GIOVANNA RIZZO (Unità di personale interno)
• ELENA FAGGIANO (Unità di personale esterno)

Prodotto

• Institute of molecular bioimaging and physiology (IBFM) (Istituto)
• Tecniche di elaborazione dati e immagini (ME.P06.005.002) (Modulo)