Automated production of copper radioisotopes and preparation of high specific activity [(64)Cu]Cu-ATSM for PET studies. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Automated production of copper radioisotopes and preparation of high specific activity [(64)Cu]Cu-ATSM for PET studies. (Articolo in rivista) (literal)

Anno

• 2010-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.apradiso.2009.08.010 (literal)

Alternative label

• Matarrese M. 1,3, Bedeschi P. 2, Scardaoni R. 3, Sudati F. 1, Savi A. 1, Pepe A. 1, Masiello V. 1, Todde S. 1, Gianolli L. 1, Messa C. 1, Fazio F. 1 (2010)
  Automated production of copper radioisotopes and preparation of high specific activity [(64)Cu]Cu-ATSM for PET studies.
  in Applied radiation and isotopes
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Matarrese M. 1,3, Bedeschi P. 2, Scardaoni R. 3, Sudati F. 1, Savi A. 1, Pepe A. 1, Masiello V. 1, Todde S. 1, Gianolli L. 1, Messa C. 1, Fazio F. 1 (literal)

Pagina inizio

• 5 (literal)

Pagina fine

• 13 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 68 (literal)

Rivista

• Applied radiation and isotopes (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• Pubblicato on-line: 25 Agosto 2009. Corresponding author: Dr. Mario Matarrese (matarrese.mario@hsr.it) IF 2010: 0.999 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 9 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1 (literal)

Note

• ISI Web of Science (WOS) (literal)
• PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1. Institute of Molecular Bioimaging and Physiology-CNR,University of Milano-Bicocca, San Raffaele Scientific Institute, Milano 2. Comecer S.p.A.,Castelbolognese (RA) 3. Technological Oncologyc Laboratory(LaTO), Cefalù (PA) (literal)

Titolo

• Automated production of copper radioisotopes and preparation of high specific activity [(64)Cu]Cu-ATSM for PET studies. (literal)

Abstract

• 60)Cu and (64)Cu are useful radioisotopes for positron emission tomography (PET) radiopharmaceuticals and may be used for the preparation of promising agents for diagnosis and radiotherapy. In this study, the production and purification of (60/64)Cu starting from (60/64)Ni using a new automated system, namely Alceo, is described. A dynamic process for electrodeposition and dissolution of (60/64)Ni/(60/64)Cu was developed. Preliminary production yields of (60)Cu and (64)Cu were 400 and 300mCi, respectively. (64)Cu was used to radiolabel the hypoxia detection tracer ATSM with a specific activity of 2.2+/-1.3Ci/mumol. (literal)

Prodotto di

• Sviluppo di radiofarmaci ad uso medico (ME.P06.006.001) (Modulo)
• Institute of molecular bioimaging and physiology (IBFM) (Istituto)

Autore CNR

• MARIA CRISTINA MESSA (Unità di personale esterno)
• VALERIA MASIELLO (Persona)
• SERGIO CAMILLO TODDE (Persona)
• MARIO MATARRESE (Persona)

Insieme di parole chiave

• Keywords of "Automated production of copper radioisotopes and preparation of high specific activity [(64)Cu]Cu-ATSM for PET studies." (Insieme di parole chiave)

Incoming links:

Autore CNR di

• MARIA CRISTINA MESSA (Unità di personale esterno)
• MARIO MATARRESE (Persona)
• VALERIA MASIELLO (Persona)
• SERGIO CAMILLO TODDE (Persona)

Prodotto

• Institute of molecular bioimaging and physiology (IBFM) (Istituto)
• Sviluppo di radiofarmaci ad uso medico (ME.P06.006.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Applied radiation and isotopes (Rivista)

Insieme di parole chiave di

• Keywords of "Automated production of copper radioisotopes and preparation of high specific activity [(64)Cu]Cu-ATSM for PET studies." (Insieme di parole chiave)