http://www.cnr.it/ontology/cnr/individuo/prodotto/ID10385
Epileptic seizures but not pseudoseizures are associated with decreased density of the serotonin transporter in blood platelet membranes (Articolo in rivista)
- Type
- Label
- Epileptic seizures but not pseudoseizures are associated with decreased density of the serotonin transporter in blood platelet membranes (Articolo in rivista) (literal)
- Anno
- 2008-01-01T00:00:00+01:00 (literal)
- Alternative label
Cupello A. 1, Audenino D. 2,3, Scarrone S. 1, Fornaro M. 2, Gatta E. 4, Fornaro P. 2, Albano C. 2 (2008)
Epileptic seizures but not pseudoseizures are associated with decreased density of the serotonin transporter in blood platelet membranes
in Neurochemical research
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Cupello A. 1, Audenino D. 2,3, Scarrone S. 1, Fornaro M. 2, Gatta E. 4, Fornaro P. 2, Albano C. 2 (literal)
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- Pubblicato on-line: 22 Aprile 2008.
Corresponding author: A. Cupello (aroldo.cupello@unige.it)
I.F.: 2.260 (literal)
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- 1. IBFM, CNR, Sezione di Genova, Genova
2. Dipartimento di Neuroscienze, Oftalmologia e Genetica, Università degli Studi, Genova
3. Reparto di Neurologia, Ospedale Civile, Vercelli
4. Dipartimento di Fisica, Università degli Studi, Genova (literal)
- Titolo
- Epileptic seizures but not pseudoseizures are associated with decreased density of the serotonin transporter in blood platelet membranes (literal)
- Abstract
- The density of the serotonin transporter in the plasma membranes of blood platelets was evaluated by labelled paroxetine binding in three different groups. These groups were: normal controls, epileptic patients having undergone a recent seizure (less than 4 days before) and patients who equally recently presented psychogenic non-epileptic seizures (pseudoseizures). Real seizures resulted in a significant decrease of membrane serotonin transporter density. In the instances of pseudoseizures, its membrane density was undistinguishable from that of normal controls. These data lend further support to the idea that down regulation of serotonin transporter may play a homeostatic role in the cessation of epileptic seizures. (literal)
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